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- NCIT_C77067 IAO_0000115 "A third generation, synthetic, water-soluble, pentapeptide analog of the marine depsipeptide dolastatin 15, with potential antimitotic and antineoplastic activities. Tasidotin and its metabolite, tasidotin C-carboxylate, suppress the dynamic instability behavior of the microtubules through a reduction of the shortening rate (disassembly); reduction of the switching frequency from growth to shortening; and by reducing microtubules growth time. This may eventually result in a reduction of cell growth." @default.
- NCIT_C77067 NCIT_A32 NCIT_C1909 @default.
- NCIT_C77067 NCIT_A5 NCIT_C142999 @default.
- NCIT_C77067 NCIT_NHC0 "C77067" @default.
- NCIT_C77067 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C77067 NCIT_P108 "Tasidotin" @default.
- NCIT_C77067 NCIT_P207 "C1610484" @default.
- NCIT_C77067 NCIT_P210 "192658-64-3" @default.
- NCIT_C77067 NCIT_P319 "05G07285DK" @default.
- NCIT_C77067 NCIT_P322 "FDA" @default.
- NCIT_C77067 NCIT_P322 "GDC" @default.
- NCIT_C77067 NCIT_P350 "C32H58N6O5" @default.
- NCIT_C77067 NCIT_P366 "Tasidotin" @default.
- NCIT_C77067 NCIT_P375 "Tasidotin" @default.
- NCIT_C77067 NCIT_R124 NCIT_C17828 @default.
- NCIT_C77067 NCIT_R124 NCIT_C20480 @default.
- NCIT_C77067 NCIT_R124 NCIT_C40795 @default.
- NCIT_C77067 NCIT_R124 NCIT_C40798 @default.
- NCIT_C77067 normalizedInformationContent "100" @default.
- NCIT_C77067 referenceCount "1" @default.
- NCIT_C77067 hasExactSynonym "ILX651" @default.
- NCIT_C77067 hasExactSynonym "TASIDOTIN" @default.
- NCIT_C77067 hasExactSynonym "Tasidotin" @default.
- NCIT_C77067 inSubset NCIT_C128784 @default.
- NCIT_C77067 inSubset NCIT_C157711 @default.
- NCIT_C77067 inSubset NCIT_C157712 @default.
- NCIT_C77067 inSubset NCIT_C177537 @default.
- NCIT_C77067 inSubset NCIT_C63923 @default.
- NCIT_C77067 type Class @default.
- NCIT_C77067 isDefinedBy ncit.owl @default.
- NCIT_C77067 label "Tasidotin" @default.
- NCIT_C77067 subClassOf NCIT_C186664 @default.
- NCIT_C77067 subClassOf NCIT_C1908 @default.
- NCIT_C77067 subClassOf NCIT_C1909 @default.
- NCIT_C77067 subClassOf NCIT_C25974 @default.
- NCIT_C77067 subClassOf NCIT_C273 @default.
- NCIT_C77067 subClassOf NCIT_C274 @default.
- NCIT_C77067 subClassOf NCIT_C77067 @default.