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- NCIT_C772 IAO_0000115 "A benzoic acid derivative with antihyperuricemic property. Probenecid competitively inhibits the active reabsorption of urate at the proximal tubule in the kidney thereby increasing urinary excretion of uric acid and lowering serum urate concentrations. This prevents urate deposition and promotes resolution of existing urate deposits. In addition, probenecid modulates the transport of organic acids and acidic drugs at the proximal and distal renal tubule, thereby increasing the drug serum concentration." @default.
- NCIT_C772 NCIT_NHC0 "C772" @default.
- NCIT_C772 NCIT_P106 "Organic Chemical" @default.
- NCIT_C772 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C772 NCIT_P108 "Probenecid" @default.
- NCIT_C772 NCIT_P175 "18786" @default.
- NCIT_C772 NCIT_P207 "C0033209" @default.
- NCIT_C772 NCIT_P210 "57-66-9" @default.
- NCIT_C772 NCIT_P319 "PO572Z7917" @default.
- NCIT_C772 NCIT_P322 "FDA" @default.
- NCIT_C772 NCIT_P325 "A drug that is used to treat gout and is used together with some antibiotics to make them work better. It is being studied in the treatment of cancer. It belongs to the family of drugs called antibiotic therapy adjuncts." @default.
- NCIT_C772 NCIT_P329 "40223" @default.
- NCIT_C772 NCIT_P330 "40223" @default.
- NCIT_C772 NCIT_P350 "C13H19NO4S" @default.
- NCIT_C772 NCIT_P366 "Probenecid" @default.
- NCIT_C772 NCIT_P399 "40223" @default.
- NCIT_C772 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C772 referenceCount "2" @default.
- NCIT_C772 hasExactSynonym "Benemid" @default.
- NCIT_C772 hasExactSynonym "PROB" @default.
- NCIT_C772 hasExactSynonym "PROBENECID" @default.
- NCIT_C772 hasExactSynonym "Probenecid" @default.
- NCIT_C772 hasExactSynonym "SK-Probenecid" @default.
- NCIT_C772 hasExactSynonym "probenecid" @default.
- NCIT_C772 inSubset NCIT_C176424 @default.
- NCIT_C772 inSubset NCIT_C63923 @default.
- NCIT_C772 type Class @default.
- NCIT_C772 isDefinedBy ncit.owl @default.
- NCIT_C772 label "Probenecid" @default.
- NCIT_C772 subClassOf NCIT_C1908 @default.
- NCIT_C772 subClassOf NCIT_C1909 @default.
- NCIT_C772 subClassOf NCIT_C26170 @default.
- NCIT_C772 subClassOf NCIT_C772 @default.
- NCIT_C772 subClassOf NCIT_C921 @default.