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- NCIT_C77333 IAO_0000115 "A steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels." @default.
- NCIT_C77333 NCIT_A32 NCIT_C1909 @default.
- NCIT_C77333 NCIT_A5 NCIT_C184796 @default.
- NCIT_C77333 NCIT_A5 NCIT_C68845 @default.
- NCIT_C77333 NCIT_A7 NCIT_C40068 @default.
- NCIT_C77333 NCIT_NHC0 "C77333" @default.
- NCIT_C77333 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C77333 NCIT_P107 "Abiraterone" @default.
- NCIT_C77333 NCIT_P108 "Abiraterone" @default.
- NCIT_C77333 NCIT_P207 "C0754011" @default.
- NCIT_C77333 NCIT_P210 "154229-19-3" @default.
- NCIT_C77333 NCIT_P319 "G819A456D0" @default.
- NCIT_C77333 NCIT_P322 "CTRP" @default.
- NCIT_C77333 NCIT_P322 "FDA" @default.
- NCIT_C77333 NCIT_P322 "GDC" @default.
- NCIT_C77333 NCIT_P322 "OORO" @default.
- NCIT_C77333 NCIT_P350 "C24H31NO" @default.
- NCIT_C77333 NCIT_P366 "Abiraterone" @default.
- NCIT_C77333 NCIT_P375 "Abiraterone" @default.
- NCIT_C77333 normalizedInformationContent "100" @default.
- NCIT_C77333 referenceCount "1" @default.
- NCIT_C77333 hasExactSynonym "17-(3-Pyridyl)androsta-5,16-dien-3beta-ol" @default.
- NCIT_C77333 hasExactSynonym "ABIRATERONE" @default.
- NCIT_C77333 hasExactSynonym "Abiraterone" @default.
- NCIT_C77333 hasExactSynonym "CB 7598" @default.
- NCIT_C77333 inSubset NCIT_C116977 @default.
- NCIT_C77333 inSubset NCIT_C116978 @default.
- NCIT_C77333 inSubset NCIT_C128784 @default.
- NCIT_C77333 inSubset NCIT_C157711 @default.
- NCIT_C77333 inSubset NCIT_C157712 @default.
- NCIT_C77333 inSubset NCIT_C177537 @default.
- NCIT_C77333 inSubset NCIT_C192234 @default.
- NCIT_C77333 inSubset NCIT_C63923 @default.
- NCIT_C77333 type Class @default.
- NCIT_C77333 isDefinedBy ncit.owl @default.
- NCIT_C77333 label "Abiraterone" @default.
- NCIT_C77333 subClassOf NCIT_C147908 @default.
- NCIT_C77333 subClassOf NCIT_C147923 @default.
- NCIT_C77333 subClassOf NCIT_C1908 @default.
- NCIT_C77333 subClassOf NCIT_C1909 @default.
- NCIT_C77333 subClassOf NCIT_C242 @default.
- NCIT_C77333 subClassOf NCIT_C471 @default.
- NCIT_C77333 subClassOf NCIT_C547 @default.
- NCIT_C77333 subClassOf NCIT_C77333 @default.