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- NCIT_C77854 IAO_0000115 "A recombinant bispecific monoclonal antibody directed against both CD3 and epithelial cell adhesion molecule (EpCAM) with potential immunomodulating and antineoplastic activities. Solitomab attaches to both CD3-expressing T lymphocytes and EpCAM-expressing tumor cells, thereby selectively cross-linking tumor and T lymphocytes; this may result in the recruitment of cytotoxic T lymphocytes (CTL) to T lymphocyte/tumor cell aggregates and the CTL-mediated death of EpCAM-expressing tumor cells. CD3 is an antigen expressed on mature T cells; EpCAM, a cell surface protein, is expressed by a variety of tumor cells and is frequently found in head and neck cancers." @default.
- NCIT_C77854 NCIT_A32 NCIT_C1909 @default.
- NCIT_C77854 NCIT_NHC0 "C77854" @default.
- NCIT_C77854 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C77854 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C77854 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C77854 NCIT_P108 "Solitomab" @default.
- NCIT_C77854 NCIT_P207 "C3642415" @default.
- NCIT_C77854 NCIT_P210 "1005198-65-1" @default.
- NCIT_C77854 NCIT_P319 "ZQQ51B5708" @default.
- NCIT_C77854 NCIT_P322 "FDA" @default.
- NCIT_C77854 NCIT_P322 "GDC" @default.
- NCIT_C77854 NCIT_P329 "592863" @default.
- NCIT_C77854 NCIT_P330 "592863" @default.
- NCIT_C77854 NCIT_P366 "Anti-EpCAM_Anti-CD3_Recombinant_Bispecific_Monoclonal_Antibody_MT110" @default.
- NCIT_C77854 NCIT_P375 "Solitomab" @default.
- NCIT_C77854 NCIT_P399 "592863" @default.
- NCIT_C77854 NCIT_R124 NCIT_C17710 @default.
- NCIT_C77854 NCIT_R124 NCIT_C17828 @default.
- NCIT_C77854 NCIT_R124 NCIT_C18219 @default.
- NCIT_C77854 NCIT_R124 NCIT_C19986 @default.
- NCIT_C77854 NCIT_R124 NCIT_C40474 @default.
- NCIT_C77854 normalizedInformationContent "100" @default.
- NCIT_C77854 referenceCount "1" @default.
- NCIT_C77854 hasExactSynonym "Anti-EpCAM BiTE" @default.
- NCIT_C77854 hasExactSynonym "MT110" @default.
- NCIT_C77854 hasExactSynonym "SOLITOMAB" @default.
- NCIT_C77854 hasExactSynonym "Solitomab" @default.
- NCIT_C77854 inSubset NCIT_C128784 @default.
- NCIT_C77854 inSubset NCIT_C157711 @default.
- NCIT_C77854 inSubset NCIT_C157712 @default.
- NCIT_C77854 inSubset NCIT_C176424 @default.
- NCIT_C77854 inSubset NCIT_C177537 @default.
- NCIT_C77854 inSubset NCIT_C63923 @default.
- NCIT_C77854 type Class @default.
- NCIT_C77854 isDefinedBy ncit.owl @default.
- NCIT_C77854 label "Solitomab" @default.
- NCIT_C77854 subClassOf NCIT_C112883 @default.
- NCIT_C77854 subClassOf NCIT_C129821 @default.
- NCIT_C77854 subClassOf NCIT_C129822 @default.
- NCIT_C77854 subClassOf NCIT_C1454 @default.
- NCIT_C77854 subClassOf NCIT_C1908 @default.
- NCIT_C77854 subClassOf NCIT_C1909 @default.
- NCIT_C77854 subClassOf NCIT_C201282 @default.
- NCIT_C77854 subClassOf NCIT_C201523 @default.
- NCIT_C77854 subClassOf NCIT_C20401 @default.
- NCIT_C77854 subClassOf NCIT_C274 @default.
- NCIT_C77854 subClassOf NCIT_C28227 @default.
- NCIT_C77854 subClassOf NCIT_C307 @default.
- NCIT_C77854 subClassOf NCIT_C308 @default.
- NCIT_C77854 subClassOf NCIT_C77854 @default.