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- NCIT_C77876 IAO_0000115 "An orally bioavailable, small-molecule, multitargeted tyrosine kinase inhibitor with potential antineoplastic activity. Glesatinib binds to and inhibits the phosphorylation of several receptor tyrosine kinases (RTKs), including the c-Met receptor (hepatocyte growth factor receptor); the Tek/Tie-2 receptor; vascular endothelial growth factor receptor (VEGFR) types 1, 2, and 3; and the macrophage-stimulating 1 receptor (MST1R or RON). Inhibition of these RTKs and their downstream signaling pathways may result in the inhibition of tumor angiogenesis and tumor cell proliferation in tumors overexpressing these RTKs." @default.
- NCIT_C77876 NCIT_A32 NCIT_C1909 @default.
- NCIT_C77876 NCIT_A7 NCIT_C17975 @default.
- NCIT_C77876 NCIT_A7 NCIT_C18186 @default.
- NCIT_C77876 NCIT_A7 NCIT_C18488 @default.
- NCIT_C77876 NCIT_A7 NCIT_C26203 @default.
- NCIT_C77876 NCIT_A7 NCIT_C28496 @default.
- NCIT_C77876 NCIT_A7 NCIT_C28526 @default.
- NCIT_C77876 NCIT_NHC0 "C77876" @default.
- NCIT_C77876 NCIT_P106 "Organic Chemical" @default.
- NCIT_C77876 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C77876 NCIT_P107 "Glesatinib" @default.
- NCIT_C77876 NCIT_P108 "Glesatinib" @default.
- NCIT_C77876 NCIT_P208 "CL383618" @default.
- NCIT_C77876 NCIT_P210 "936694-12-1" @default.
- NCIT_C77876 NCIT_P319 "7Q29OXD98N" @default.
- NCIT_C77876 NCIT_P322 "CTRP" @default.
- NCIT_C77876 NCIT_P322 "FDA" @default.
- NCIT_C77876 NCIT_P322 "GDC" @default.
- NCIT_C77876 NCIT_P329 "597305" @default.
- NCIT_C77876 NCIT_P330 "597305" @default.
- NCIT_C77876 NCIT_P366 "Tyrosine_Kinase_Inhibitor_MGCD265" @default.
- NCIT_C77876 NCIT_P375 "Glesatinib" @default.
- NCIT_C77876 NCIT_P399 "597305" @default.
- NCIT_C77876 normalizedInformationContent "100" @default.
- NCIT_C77876 referenceCount "1" @default.
- NCIT_C77876 hasExactSynonym "GLESATINIB" @default.
- NCIT_C77876 hasExactSynonym "Glesatinib" @default.
- NCIT_C77876 hasExactSynonym "MG90265" @default.
- NCIT_C77876 hasExactSynonym "MG90265X" @default.
- NCIT_C77876 hasExactSynonym "MGCD265" @default.
- NCIT_C77876 hasExactSynonym "TKI MGCD265" @default.
- NCIT_C77876 inSubset NCIT_C116977 @default.
- NCIT_C77876 inSubset NCIT_C116978 @default.
- NCIT_C77876 inSubset NCIT_C128784 @default.
- NCIT_C77876 inSubset NCIT_C157711 @default.
- NCIT_C77876 inSubset NCIT_C157712 @default.
- NCIT_C77876 inSubset NCIT_C176424 @default.
- NCIT_C77876 inSubset NCIT_C177537 @default.
- NCIT_C77876 inSubset NCIT_C63923 @default.
- NCIT_C77876 type Class @default.
- NCIT_C77876 isDefinedBy ncit.owl @default.
- NCIT_C77876 label "Glesatinib" @default.
- NCIT_C77876 subClassOf NCIT_C129824 @default.
- NCIT_C77876 subClassOf NCIT_C129825 @default.
- NCIT_C77876 subClassOf NCIT_C1404 @default.
- NCIT_C77876 subClassOf NCIT_C1908 @default.
- NCIT_C77876 subClassOf NCIT_C1909 @default.
- NCIT_C77876 subClassOf NCIT_C1967 @default.
- NCIT_C77876 subClassOf NCIT_C2189 @default.
- NCIT_C77876 subClassOf NCIT_C274 @default.
- NCIT_C77876 subClassOf NCIT_C471 @default.
- NCIT_C77876 subClassOf NCIT_C77876 @default.