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- NCIT_C78187 IAO_0000115 "A glycoengineered, fully human IgG1 monoclonal antibody directed against the extracellular domain of the human CD70 molecule with potential antineoplastic activity. Anti-CD70 fully human monoclonal antibody MDX-1411 selectivity binds to the extracellular domain of CD70, which may induce an antibody-dependent cellular cytotoxicity (ADCC) response against CD70-expressing tumor cells. CD70, the ligand for the costimulatory receptor CD27 and a member of the tumor necrosis factor (TNF) family, is found on renal cell carcinoma (RCC) cells among other cancer cell types." @default.
- NCIT_C78187 NCIT_A32 NCIT_C1909 @default.
- NCIT_C78187 NCIT_A7 NCIT_C104079 @default.
- NCIT_C78187 NCIT_NHC0 "C78187" @default.
- NCIT_C78187 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C78187 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C78187 NCIT_P107 "Anti-CD70 Monoclonal Antibody MDX-1411" @default.
- NCIT_C78187 NCIT_P108 "Anti-CD70 Monoclonal Antibody MDX-1411" @default.
- NCIT_C78187 NCIT_P208 "CL383579" @default.
- NCIT_C78187 NCIT_P322 "CTRP" @default.
- NCIT_C78187 NCIT_P322 "GDC" @default.
- NCIT_C78187 NCIT_P329 "594769" @default.
- NCIT_C78187 NCIT_P330 "594769" @default.
- NCIT_C78187 NCIT_P366 "Anti-CD70_Fully_Human_Monoclonal_Antibody_MDX-1411" @default.
- NCIT_C78187 NCIT_P375 "Anti-CD70 Monoclonal Antibody MDX-1411" @default.
- NCIT_C78187 NCIT_P399 "594769" @default.
- NCIT_C78187 NCIT_R124 NCIT_C17710 @default.
- NCIT_C78187 NCIT_R124 NCIT_C17828 @default.
- NCIT_C78187 NCIT_R124 NCIT_C18219 @default.
- NCIT_C78187 NCIT_R124 NCIT_C19986 @default.
- NCIT_C78187 NCIT_R124 NCIT_C40474 @default.
- NCIT_C78187 normalizedInformationContent "100" @default.
- NCIT_C78187 referenceCount "1" @default.
- NCIT_C78187 hasExactSynonym "Anti-CD70 Monoclonal Antibody MDX-1411" @default.
- NCIT_C78187 hasExactSynonym "MDX-1411" @default.
- NCIT_C78187 inSubset NCIT_C116977 @default.
- NCIT_C78187 inSubset NCIT_C116978 @default.
- NCIT_C78187 inSubset NCIT_C128784 @default.
- NCIT_C78187 inSubset NCIT_C157711 @default.
- NCIT_C78187 inSubset NCIT_C157712 @default.
- NCIT_C78187 inSubset NCIT_C176424 @default.
- NCIT_C78187 inSubset NCIT_C177537 @default.
- NCIT_C78187 type Class @default.
- NCIT_C78187 isDefinedBy ncit.owl @default.
- NCIT_C78187 label "Anti-CD70 Monoclonal Antibody MDX-1411" @default.
- NCIT_C78187 subClassOf NCIT_C129821 @default.
- NCIT_C78187 subClassOf NCIT_C129822 @default.
- NCIT_C78187 subClassOf NCIT_C163758 @default.
- NCIT_C78187 subClassOf NCIT_C1908 @default.
- NCIT_C78187 subClassOf NCIT_C1909 @default.
- NCIT_C78187 subClassOf NCIT_C192643 @default.
- NCIT_C78187 subClassOf NCIT_C200042 @default.
- NCIT_C78187 subClassOf NCIT_C20401 @default.
- NCIT_C78187 subClassOf NCIT_C274 @default.
- NCIT_C78187 subClassOf NCIT_C307 @default.
- NCIT_C78187 subClassOf NCIT_C308 @default.
- NCIT_C78187 subClassOf NCIT_C78187 @default.