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- NCIT_C78227 IAO_0000115 "Along with the immunoglobulin G3 subclass (IgG3), this IgG subtype makes up a minor part of circulating antibodies in healthy individuals. The IgG4 core hinge sequence contains 12 amino acids and two interchain disulfide bonds.This subtype has moderate affinity for binding Fc receptors and does not bind complement component C1q. The production of IgG4 can be stimulated following repeated or long-term exposure to antigen. Elevated levels are found in various diseases and infections and can be indicative of an fibroinflammatory syndrome known as IgG4-related disease." @default.
- NCIT_C78227 NCIT_NHC0 "C78227" @default.
- NCIT_C78227 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C78227 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C78227 NCIT_P108 "IgG4" @default.
- NCIT_C78227 NCIT_P171 "25368619" @default.
- NCIT_C78227 NCIT_P207 "C0020860" @default.
- NCIT_C78227 NCIT_P366 "IgG4" @default.
- NCIT_C78227 NCIT_R44 NCIT_C21176 @default.
- NCIT_C78227 NCIT_R44 NCIT_C26548 @default.
- NCIT_C78227 NCIT_R52 NCIT_C16295 @default.
- NCIT_C78227 NCIT_R52 NCIT_C16725 @default.
- NCIT_C78227 NCIT_R52 NCIT_C17021 @default.
- NCIT_C78227 NCIT_R52 NCIT_C20027 @default.
- NCIT_C78227 NCIT_R52 NCIT_C26548 @default.
- NCIT_C78227 NCIT_R53 NCIT_C17710 @default.
- NCIT_C78227 NCIT_R53 NCIT_C17828 @default.
- NCIT_C78227 NCIT_R53 NCIT_C17930 @default.
- NCIT_C78227 NCIT_R53 NCIT_C17937 @default.
- NCIT_C78227 NCIT_R53 NCIT_C18219 @default.
- NCIT_C78227 NCIT_R53 NCIT_C18839 @default.
- NCIT_C78227 NCIT_R53 NCIT_C19986 @default.
- NCIT_C78227 NCIT_R53 NCIT_C21124 @default.
- NCIT_C78227 NCIT_R53 NCIT_C40474 @default.
- NCIT_C78227 NCIT_R54 NCIT_C16612 @default.
- NCIT_C78227 NCIT_R54 NCIT_C25790 @default.
- NCIT_C78227 normalizedInformationContent "100" @default.
- NCIT_C78227 referenceCount "1" @default.
- NCIT_C78227 hasExactSynonym "IgG4" @default.
- NCIT_C78227 hasExactSynonym "Immunoglobulin G Subclass 4" @default.
- NCIT_C78227 hasExactSynonym "Immunoglobulin G4" @default.
- NCIT_C78227 type Class @default.
- NCIT_C78227 isDefinedBy ncit.owl @default.
- NCIT_C78227 label "IgG4" @default.
- NCIT_C78227 subClassOf NCIT_C16295 @default.
- NCIT_C78227 subClassOf NCIT_C16725 @default.
- NCIT_C78227 subClassOf NCIT_C17021 @default.
- NCIT_C78227 subClassOf NCIT_C20027 @default.
- NCIT_C78227 subClassOf NCIT_C26548 @default.
- NCIT_C78227 subClassOf NCIT_C568 @default.
- NCIT_C78227 subClassOf NCIT_C572 @default.
- NCIT_C78227 subClassOf NCIT_C78227 @default.