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- NCIT_C78830 IAO_0000115 "A cancer vaccine consisting of autologous, mature monocyte-derived dendritic cells (DCs) transfected with oncofetal antigen immature laminin receptor protein (OFA-iLRP) RNA, with potential antineoplastic activity. Upon administration, DCs in the OFA-iLRP RNA-transfected autologous dendritic cell vaccine express, process, and present OFA-iLRP to the host immune system, which may mount a potent cytotoxic T-cell (CTL) response against OFA-iLRP-expressing tumor cells. As a highly conserved protein, OFA-iLRP is preferentially expressed in fetal tissues and in many types of cancer, including hematopoietic malignancies, but is not detectable in normal differentiated adult cells." @default.
- NCIT_C78830 NCIT_NHC0 "C78830" @default.
- NCIT_C78830 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C78830 NCIT_P108 "Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine" @default.
- NCIT_C78830 NCIT_P208 "CL387729" @default.
- NCIT_C78830 NCIT_P329 "601895" @default.
- NCIT_C78830 NCIT_P330 "601895" @default.
- NCIT_C78830 NCIT_P366 "OFA-iLRP-Loaded_Autologous_Dendritic_Cell_Vaccine" @default.
- NCIT_C78830 NCIT_P399 "601895" @default.
- NCIT_C78830 normalizedInformationContent "100" @default.
- NCIT_C78830 referenceCount "1" @default.
- NCIT_C78830 hasExactSynonym "Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine" @default.
- NCIT_C78830 inSubset NCIT_C128784 @default.
- NCIT_C78830 inSubset NCIT_C176424 @default.
- NCIT_C78830 type Class @default.
- NCIT_C78830 isDefinedBy ncit.owl @default.
- NCIT_C78830 label "Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine" @default.
- NCIT_C78830 subClassOf NCIT_C129820 @default.
- NCIT_C78830 subClassOf NCIT_C1663 @default.
- NCIT_C78830 subClassOf NCIT_C172787 @default.
- NCIT_C78830 subClassOf NCIT_C181141 @default.
- NCIT_C78830 subClassOf NCIT_C1908 @default.
- NCIT_C78830 subClassOf NCIT_C1909 @default.
- NCIT_C78830 subClassOf NCIT_C274 @default.
- NCIT_C78830 subClassOf NCIT_C28308 @default.
- NCIT_C78830 subClassOf NCIT_C28310 @default.
- NCIT_C78830 subClassOf NCIT_C307 @default.
- NCIT_C78830 subClassOf NCIT_C308 @default.
- NCIT_C78830 subClassOf NCIT_C78830 @default.
- NCIT_C78830 subClassOf NCIT_C923 @default.