Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C78832> ?p ?o ?g. }
Showing items 1 to 35 of
35
with 100 items per page.
- NCIT_C78832 IAO_0000115 "A whole-cell cancer vaccine, containing human acute myeloid leukemic (AML) blasts that have been genetically engineered to express a B7.1/IIL-2 fusion protein encoded by a self-inactivating lentiviral vector (LV), with potential antineoplastic and immunomodulating activities. Upon administration, LV.IL-2/B7.1-transduced AML blast vaccine RFUSIN2-AML1 may stimulate a host cytotoxic T lymphocyte (CTL) response against AML cells. The single fusion protein encoded by the LV is postsynthetically cleaved to produce biologically active membrane-anchored B7.1 and secreted IL-2 in AML blasts; combined expression of IL-2 and the co-stimulatory molecule B7.1 by AML blasts may increase stimulation of both allogeneic and autologous cytotoxic T cells." @default.
- NCIT_C78832 NCIT_A32 NCIT_C1909 @default.
- NCIT_C78832 NCIT_NHC0 "C78832" @default.
- NCIT_C78832 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C78832 NCIT_P108 "LV.IL-2/B7.1-Transduced AML Blast Vaccine RFUSIN2-AML1" @default.
- NCIT_C78832 NCIT_P208 "CL387720" @default.
- NCIT_C78832 NCIT_P322 "GDC" @default.
- NCIT_C78832 NCIT_P329 "609860" @default.
- NCIT_C78832 NCIT_P330 "609860" @default.
- NCIT_C78832 NCIT_P366 "LV_IL-2_B7_1-Transduced_AML_Blast_Vaccine" @default.
- NCIT_C78832 NCIT_P375 "LV.IL-2/B7.1-Transduced AML Blast Vaccine RFUSIN2-AML1" @default.
- NCIT_C78832 NCIT_P399 "609860" @default.
- NCIT_C78832 normalizedInformationContent "100" @default.
- NCIT_C78832 referenceCount "1" @default.
- NCIT_C78832 hasExactSynonym "LV.IL-2/B7.1-Transduced AML Blast Vaccine RFUSIN2-AML1" @default.
- NCIT_C78832 hasExactSynonym "Lentivirus-transduced AML Blasts Expressing B7.1 and IL-2" @default.
- NCIT_C78832 hasExactSynonym "RFUSIN2-AML1" @default.
- NCIT_C78832 inSubset NCIT_C128784 @default.
- NCIT_C78832 inSubset NCIT_C157711 @default.
- NCIT_C78832 inSubset NCIT_C157712 @default.
- NCIT_C78832 inSubset NCIT_C176424 @default.
- NCIT_C78832 inSubset NCIT_C177537 @default.
- NCIT_C78832 type Class @default.
- NCIT_C78832 isDefinedBy ncit.owl @default.
- NCIT_C78832 label "LV.IL-2/B7.1-Transduced AML Blast Vaccine RFUSIN2-AML1" @default.
- NCIT_C78832 subClassOf NCIT_C129820 @default.
- NCIT_C78832 subClassOf NCIT_C1663 @default.
- NCIT_C78832 subClassOf NCIT_C1908 @default.
- NCIT_C78832 subClassOf NCIT_C1909 @default.
- NCIT_C78832 subClassOf NCIT_C2341 @default.
- NCIT_C78832 subClassOf NCIT_C274 @default.
- NCIT_C78832 subClassOf NCIT_C307 @default.
- NCIT_C78832 subClassOf NCIT_C308 @default.
- NCIT_C78832 subClassOf NCIT_C78832 @default.
- NCIT_C78832 subClassOf NCIT_C923 @default.