Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C78853> ?p ?o ?g. }
Showing items 1 to 52 of
52
with 100 items per page.
- NCIT_C78853 IAO_0000115 "A fully human monoclonal antibody directed against the membrane-bound receptor HER3 (ERBB3) with potential antineoplastic activity. Patritumab binds to and inhibits HER3 activation, which may result in inhibition of HER3-dependent PI3K/Akt signaling and so inhibition of cellular proliferation and differentiation. HER3, a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases, is frequently overexpressed in solid tumors, including breast, lung, and colorectal tumors of epithelial origin; it has no active kinase domain itself but is activated through heterodimerization with other members of the EGFR receptor family that do." @default.
- NCIT_C78853 NCIT_A32 NCIT_C1909 @default.
- NCIT_C78853 NCIT_A7 NCIT_C18490 @default.
- NCIT_C78853 NCIT_NHC0 "C78853" @default.
- NCIT_C78853 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C78853 NCIT_P107 "Patritumab" @default.
- NCIT_C78853 NCIT_P108 "Patritumab" @default.
- NCIT_C78853 NCIT_P207 "C2698144" @default.
- NCIT_C78853 NCIT_P210 "1262787-83-6" @default.
- NCIT_C78853 NCIT_P319 "86780VJI1Q" @default.
- NCIT_C78853 NCIT_P322 "CTRP" @default.
- NCIT_C78853 NCIT_P322 "FDA" @default.
- NCIT_C78853 NCIT_P322 "GDC" @default.
- NCIT_C78853 NCIT_P329 "612849" @default.
- NCIT_C78853 NCIT_P330 "612849" @default.
- NCIT_C78853 NCIT_P366 "Anti-HER3_Monoclonal_Antibody_U3-1287" @default.
- NCIT_C78853 NCIT_P375 "Patritumab" @default.
- NCIT_C78853 NCIT_P399 "612849" @default.
- NCIT_C78853 NCIT_R124 NCIT_C17710 @default.
- NCIT_C78853 NCIT_R124 NCIT_C17828 @default.
- NCIT_C78853 NCIT_R124 NCIT_C18219 @default.
- NCIT_C78853 NCIT_R124 NCIT_C19986 @default.
- NCIT_C78853 NCIT_R124 NCIT_C40474 @default.
- NCIT_C78853 normalizedInformationContent "100" @default.
- NCIT_C78853 referenceCount "1" @default.
- NCIT_C78853 hasExactSynonym "AMG 888" @default.
- NCIT_C78853 hasExactSynonym "PATRITUMAB" @default.
- NCIT_C78853 hasExactSynonym "Patritumab" @default.
- NCIT_C78853 hasExactSynonym "U3-1287" @default.
- NCIT_C78853 inSubset NCIT_C116977 @default.
- NCIT_C78853 inSubset NCIT_C116978 @default.
- NCIT_C78853 inSubset NCIT_C128784 @default.
- NCIT_C78853 inSubset NCIT_C157711 @default.
- NCIT_C78853 inSubset NCIT_C157712 @default.
- NCIT_C78853 inSubset NCIT_C176424 @default.
- NCIT_C78853 inSubset NCIT_C177537 @default.
- NCIT_C78853 inSubset NCIT_C63923 @default.
- NCIT_C78853 type Class @default.
- NCIT_C78853 isDefinedBy ncit.owl @default.
- NCIT_C78853 label "Patritumab" @default.
- NCIT_C78853 subClassOf NCIT_C129821 @default.
- NCIT_C78853 subClassOf NCIT_C129822 @default.
- NCIT_C78853 subClassOf NCIT_C163758 @default.
- NCIT_C78853 subClassOf NCIT_C1908 @default.
- NCIT_C78853 subClassOf NCIT_C1909 @default.
- NCIT_C78853 subClassOf NCIT_C199383 @default.
- NCIT_C78853 subClassOf NCIT_C199386 @default.
- NCIT_C78853 subClassOf NCIT_C20401 @default.
- NCIT_C78853 subClassOf NCIT_C274 @default.
- NCIT_C78853 subClassOf NCIT_C307 @default.
- NCIT_C78853 subClassOf NCIT_C308 @default.
- NCIT_C78853 subClassOf NCIT_C78853 @default.