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- NCIT_C79761 IAO_0000115 "The phenyl ester of carbenicillin, a broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Following absorption, carbenicillin phenyl sodium is rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually causing bacterial cell lysis." @default.
- NCIT_C79761 NCIT_NHC0 "C79761" @default.
- NCIT_C79761 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C79761 NCIT_P108 "Carbenicillin Phenyl" @default.
- NCIT_C79761 NCIT_P207 "C2698988" @default.
- NCIT_C79761 NCIT_P210 "27025-49-6" @default.
- NCIT_C79761 NCIT_P319 "9UU4XDB74X" @default.
- NCIT_C79761 NCIT_P322 "FDA" @default.
- NCIT_C79761 NCIT_P350 "C23H22N2O6S" @default.
- NCIT_C79761 NCIT_P366 "Carbenicillin_Phenyl" @default.
- NCIT_C79761 NCIT_P368 "CHEBI:3414" @default.
- NCIT_C79761 normalizedInformationContent "100" @default.
- NCIT_C79761 referenceCount "1" @default.
- NCIT_C79761 hasExactSynonym "(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((2-phenoxycarbonyl)-2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptan-2-carbonsaeure" @default.
- NCIT_C79761 hasExactSynonym "CARBENICILLIN PHENYL" @default.
- NCIT_C79761 hasExactSynonym "Carbenicillin Phenyl" @default.
- NCIT_C79761 inSubset NCIT_C63923 @default.
- NCIT_C79761 type Class @default.
- NCIT_C79761 isDefinedBy ncit.owl @default.
- NCIT_C79761 label "Carbenicillin Phenyl" @default.
- NCIT_C79761 subClassOf NCIT_C1500 @default.
- NCIT_C79761 subClassOf NCIT_C1908 @default.
- NCIT_C79761 subClassOf NCIT_C1909 @default.
- NCIT_C79761 subClassOf NCIT_C254 @default.
- NCIT_C79761 subClassOf NCIT_C258 @default.
- NCIT_C79761 subClassOf NCIT_C260 @default.
- NCIT_C79761 subClassOf NCIT_C79761 @default.