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- NCIT_C801 IAO_0000115 "An orally bioavailable bis-dioxopiperazine and a derivative of the chelating agent ethylenediaminetetraacetic acid (EDTA) with antineoplastic, antiangiogenic, and antimetastatic activities. Razoxane specifically inhibits the enzyme topoisomerase II without inducing DNA strand breaks, which may result in the inhibition of DNA synthesis and cell division in the premitotic and early mitotic phases of the cell cycle. This agent may also exhibit antiangiogenic and antimetastatic activities although the precise molecular mechanisms of these actions are unknown." @default.
- NCIT_C801 NCIT_A32 NCIT_C1909 @default.
- NCIT_C801 NCIT_NHC0 "C801" @default.
- NCIT_C801 NCIT_P106 "Organic Chemical" @default.
- NCIT_C801 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C801 NCIT_P108 "Razoxane" @default.
- NCIT_C801 NCIT_P175 "129943" @default.
- NCIT_C801 NCIT_P207 "C0034738" @default.
- NCIT_C801 NCIT_P210 "21416-67-1" @default.
- NCIT_C801 NCIT_P210 "21416-87-5" @default.
- NCIT_C801 NCIT_P319 "5AR83PR647" @default.
- NCIT_C801 NCIT_P322 "FDA" @default.
- NCIT_C801 NCIT_P322 "GDC" @default.
- NCIT_C801 NCIT_P329 "39480" @default.
- NCIT_C801 NCIT_P330 "39480" @default.
- NCIT_C801 NCIT_P350 "C11H16N4O4" @default.
- NCIT_C801 NCIT_P366 "Razoxane" @default.
- NCIT_C801 NCIT_P368 "CHEBI:50225" @default.
- NCIT_C801 NCIT_P375 "Razoxane" @default.
- NCIT_C801 NCIT_P399 "39480" @default.
- NCIT_C801 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C801 referenceCount "2" @default.
- NCIT_C801 hasExactSynonym "ICI 59118" @default.
- NCIT_C801 hasExactSynonym "ICRF 159" @default.
- NCIT_C801 hasExactSynonym "ICRF-159" @default.
- NCIT_C801 hasExactSynonym "ICRF159" @default.
- NCIT_C801 hasExactSynonym "RAZOXANE" @default.
- NCIT_C801 hasExactSynonym "Razoxane" @default.
- NCIT_C801 hasExactSynonym "Razoxin" @default.
- NCIT_C801 inSubset NCIT_C128784 @default.
- NCIT_C801 inSubset NCIT_C157711 @default.
- NCIT_C801 inSubset NCIT_C157712 @default.
- NCIT_C801 inSubset NCIT_C176424 @default.
- NCIT_C801 inSubset NCIT_C177537 @default.
- NCIT_C801 inSubset NCIT_C63923 @default.
- NCIT_C801 type Class @default.
- NCIT_C801 isDefinedBy ncit.owl @default.
- NCIT_C801 label "Razoxane" @default.
- NCIT_C801 subClassOf NCIT_C1908 @default.
- NCIT_C801 subClassOf NCIT_C1932 @default.
- NCIT_C801 subClassOf NCIT_C360 @default.
- NCIT_C801 subClassOf NCIT_C801 @default.