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- NCIT_C80327 IAO_0000115 "The hydrochloride salt of a saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), safingol competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo." @default.
- NCIT_C80327 NCIT_A6 NCIT_C1568 @default.
- NCIT_C80327 NCIT_NHC0 "C80327" @default.
- NCIT_C80327 NCIT_P106 "Organic Chemical" @default.
- NCIT_C80327 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C80327 NCIT_P108 "Safingol Hydrochloride" @default.
- NCIT_C80327 NCIT_P207 "C0888599" @default.
- NCIT_C80327 NCIT_P210 "139755-79-6" @default.
- NCIT_C80327 NCIT_P319 "30MA50WJ4N" @default.
- NCIT_C80327 NCIT_P322 "FDA" @default.
- NCIT_C80327 NCIT_P350 "C18H39NO2.HCl" @default.
- NCIT_C80327 NCIT_P366 "Safingol_Hydrochloride" @default.
- NCIT_C80327 NCIT_R124 NCIT_C17710 @default.
- NCIT_C80327 NCIT_R124 NCIT_C17828 @default.
- NCIT_C80327 NCIT_R124 NCIT_C28498 @default.
- NCIT_C80327 NCIT_R124 NCIT_C40576 @default.
- NCIT_C80327 NCIT_R124 NCIT_C40577 @default.
- NCIT_C80327 NCIT_R125 NCIT_C17828 @default.
- NCIT_C80327 NCIT_R125 NCIT_C20150 @default.
- NCIT_C80327 NCIT_R125 NCIT_C20480 @default.
- NCIT_C80327 NCIT_R125 NCIT_C40715 @default.
- NCIT_C80327 NCIT_R125 NCIT_C41515 @default.
- NCIT_C80327 NCIT_R125 NCIT_C51037 @default.
- NCIT_C80327 NCIT_R146 NCIT_C17017 @default.
- NCIT_C80327 NCIT_R146 NCIT_C21176 @default.
- NCIT_C80327 NCIT_R146 NCIT_C26548 @default.
- NCIT_C80327 normalizedInformationContent "100" @default.
- NCIT_C80327 referenceCount "1" @default.
- NCIT_C80327 hasExactSynonym "(2S,3S)-2-Amino-1,3-Octadecanediol Hydrochloride" @default.
- NCIT_C80327 hasExactSynonym "1,3-Octadecanediol, 2-amino-, Hydrochloride, (S-(R*,R*))-" @default.
- NCIT_C80327 hasExactSynonym "SAFINGOL HYDROCHLORIDE" @default.
- NCIT_C80327 hasExactSynonym "SPC-100271" @default.
- NCIT_C80327 hasExactSynonym "Safingol HCl" @default.
- NCIT_C80327 hasExactSynonym "Safingol Hydrochloride" @default.
- NCIT_C80327 inSubset NCIT_C63923 @default.
- NCIT_C80327 type Class @default.
- NCIT_C80327 isDefinedBy ncit.owl @default.
- NCIT_C80327 label "Safingol Hydrochloride" @default.
- NCIT_C80327 subClassOf B28ae8ff4994da9a36d7789e92d384652 @default.
- NCIT_C80327 subClassOf B7cbc644a97e8988f0e86cf73bf25db0a @default.
- NCIT_C80327 subClassOf Bb11d5a109c307f4f9b04de2edc6f8d22 @default.
- NCIT_C80327 subClassOf Bed7db2a4ad50d83e7d3c97aada799b3b @default.
- NCIT_C80327 subClassOf Bee6c361417c5af79def1af07c06363ee @default.
- NCIT_C80327 subClassOf Bef88ef640f19cc1cca5d119d9961a9e1 @default.
- NCIT_C80327 subClassOf NCIT_C1404 @default.
- NCIT_C80327 subClassOf NCIT_C1908 @default.
- NCIT_C80327 subClassOf NCIT_C1909 @default.
- NCIT_C80327 subClassOf NCIT_C2089 @default.
- NCIT_C80327 subClassOf NCIT_C471 @default.
- NCIT_C80327 subClassOf NCIT_C61074 @default.
- NCIT_C80327 subClassOf NCIT_C80327 @default.