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- NCIT_C80692 IAO_0000115 "The sodium salt of the prodrug rabeprazole, a substituted benzimidazole proton pump inhibitor, with potential anti-ulcer activity. After protonation, accumulation, and transformation to the active sulfenamide within the acidic environment of gastric parietal cells, rabeprazole selectively and irreversibly binds to and inhibits the H+, K+ATPase (hydrogen-potassium adenosine triphosphatase) enzyme system located on the parietal cell secretory surface, inhibiting gastric acid secretion." @default.
- NCIT_C80692 NCIT_A6 NCIT_C29410 @default.
- NCIT_C80692 NCIT_NHC0 "C80692" @default.
- NCIT_C80692 NCIT_P106 "Organic Chemical" @default.
- NCIT_C80692 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C80692 NCIT_P108 "Rabeprazole Sodium" @default.
- NCIT_C80692 NCIT_P207 "C0732569" @default.
- NCIT_C80692 NCIT_P210 "117976-90-6" @default.
- NCIT_C80692 NCIT_P319 "3L36P16U4R" @default.
- NCIT_C80692 NCIT_P322 "FDA" @default.
- NCIT_C80692 NCIT_P329 "641009" @default.
- NCIT_C80692 NCIT_P330 "641009" @default.
- NCIT_C80692 NCIT_P350 "C18H20N3O3S.Na" @default.
- NCIT_C80692 NCIT_P366 "Rabeprazole_Sodium" @default.
- NCIT_C80692 NCIT_P368 "CHEBI:8769" @default.
- NCIT_C80692 NCIT_P399 "641009" @default.
- NCIT_C80692 normalizedInformationContent "100" @default.
- NCIT_C80692 referenceCount "1" @default.
- NCIT_C80692 hasExactSynonym "2-(((4-(3-Methoxypropoxy)-3-methyl-2-pyridyl)methyl)sulfinyl)benzimidazole Sodium Salt" @default.
- NCIT_C80692 hasExactSynonym "Aciphex" @default.
- NCIT_C80692 hasExactSynonym "E-3810" @default.
- NCIT_C80692 hasExactSynonym "LY 307640 Sodium" @default.
- NCIT_C80692 hasExactSynonym "Pariet" @default.
- NCIT_C80692 hasExactSynonym "RABEPRAZOLE SODIUM" @default.
- NCIT_C80692 hasExactSynonym "Rabeprazole Sodium" @default.
- NCIT_C80692 hasExactSynonym "Rablet" @default.
- NCIT_C80692 inSubset NCIT_C176424 @default.
- NCIT_C80692 inSubset NCIT_C63923 @default.
- NCIT_C80692 type Class @default.
- NCIT_C80692 isDefinedBy ncit.owl @default.
- NCIT_C80692 label "Rabeprazole Sodium" @default.
- NCIT_C80692 subClassOf NCIT_C1908 @default.
- NCIT_C80692 subClassOf NCIT_C1909 @default.
- NCIT_C80692 subClassOf NCIT_C29701 @default.
- NCIT_C80692 subClassOf NCIT_C29723 @default.
- NCIT_C80692 subClassOf NCIT_C78276 @default.
- NCIT_C80692 subClassOf NCIT_C80692 @default.