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- NCIT_C80867 IAO_0000115 "An orally bioavailable indole ether quinazoline derivative and vascular endothelial growth factor receptor (VEGFR) inhibitor, with potential antineoplastic activity. Upon oral administration, cediranib binds to and inhibits the three VEGFR subtypes 1 (VEGFR-1), 2 (VEGFR-2) and 3 (VEGFR-3), thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth. Expression of VEGFRs may be upregulated in a variety of tumor cell types." @default.
- NCIT_C80867 NCIT_A32 NCIT_C1909 @default.
- NCIT_C80867 NCIT_A5 NCIT_C48379 @default.
- NCIT_C80867 NCIT_A7 NCIT_C17975 @default.
- NCIT_C80867 NCIT_A7 NCIT_C26203 @default.
- NCIT_C80867 NCIT_A7 NCIT_C28496 @default.
- NCIT_C80867 NCIT_NHC0 "C80867" @default.
- NCIT_C80867 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C80867 NCIT_P107 "Cediranib" @default.
- NCIT_C80867 NCIT_P108 "Cediranib" @default.
- NCIT_C80867 NCIT_P207 "C1698364" @default.
- NCIT_C80867 NCIT_P210 "288383-20-0" @default.
- NCIT_C80867 NCIT_P319 "NQU9IPY4K9" @default.
- NCIT_C80867 NCIT_P322 "CTRP" @default.
- NCIT_C80867 NCIT_P322 "FDA" @default.
- NCIT_C80867 NCIT_P322 "GDC" @default.
- NCIT_C80867 NCIT_P350 "C25H27FN4O3" @default.
- NCIT_C80867 NCIT_P366 "Cediranib" @default.
- NCIT_C80867 NCIT_P375 "Cediranib" @default.
- NCIT_C80867 normalizedInformationContent "100" @default.
- NCIT_C80867 referenceCount "1" @default.
- NCIT_C80867 hasExactSynonym "4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline" @default.
- NCIT_C80867 hasExactSynonym "AZ-D2171" @default.
- NCIT_C80867 hasExactSynonym "AZD2171" @default.
- NCIT_C80867 hasExactSynonym "CEDIRANIB" @default.
- NCIT_C80867 hasExactSynonym "Cediranib" @default.
- NCIT_C80867 inSubset NCIT_C116977 @default.
- NCIT_C80867 inSubset NCIT_C116978 @default.
- NCIT_C80867 inSubset NCIT_C128784 @default.
- NCIT_C80867 inSubset NCIT_C157711 @default.
- NCIT_C80867 inSubset NCIT_C157712 @default.
- NCIT_C80867 inSubset NCIT_C177537 @default.
- NCIT_C80867 inSubset NCIT_C63923 @default.
- NCIT_C80867 type Class @default.
- NCIT_C80867 isDefinedBy ncit.owl @default.
- NCIT_C80867 label "Cediranib" @default.
- NCIT_C80867 subClassOf NCIT_C1404 @default.
- NCIT_C80867 subClassOf NCIT_C1742 @default.
- NCIT_C80867 subClassOf NCIT_C1908 @default.
- NCIT_C80867 subClassOf NCIT_C1909 @default.
- NCIT_C80867 subClassOf NCIT_C1967 @default.
- NCIT_C80867 subClassOf NCIT_C274 @default.
- NCIT_C80867 subClassOf NCIT_C471 @default.
- NCIT_C80867 subClassOf NCIT_C80867 @default.