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- NCIT_C80963 IAO_0000115 "The sodium salt form of ditiocarb, an active metabolite of disulfiram, with potential antineoplastic and chemosensitizing activities. Upon administration, ditiocarb sodium may form a complex with copper (Cu), a metal that selectively accumulates in cancer cells. This complex may inhibit the nuclear factor-kB (NF-kB) pathway activated by tumor hypoxia, thereby inhibiting tumor cell growth. It may also reverse chemoresistance and enhance cytotoxicity of other chemotherapeutic agents." @default.
- NCIT_C80963 NCIT_NHC0 "C80963" @default.
- NCIT_C80963 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C80963 NCIT_P108 "Ditiocarb Sodium" @default.
- NCIT_C80963 NCIT_P175 "38583" @default.
- NCIT_C80963 NCIT_P207 "C0700086" @default.
- NCIT_C80963 NCIT_P210 "148-18-5" @default.
- NCIT_C80963 NCIT_P319 "A5304YEB5E" @default.
- NCIT_C80963 NCIT_P322 "FDA" @default.
- NCIT_C80963 NCIT_P329 "802912" @default.
- NCIT_C80963 NCIT_P330 "802912" @default.
- NCIT_C80963 NCIT_P350 "C5H10NS2.Na" @default.
- NCIT_C80963 NCIT_P366 "Ditiocarb_Sodium" @default.
- NCIT_C80963 NCIT_P399 "802912" @default.
- NCIT_C80963 normalizedInformationContent "100" @default.
- NCIT_C80963 referenceCount "1" @default.
- NCIT_C80963 hasExactSynonym "DITIOCARB SODIUM" @default.
- NCIT_C80963 hasExactSynonym "Diethylcarbamodithioic Acid, Sodium Salt" @default.
- NCIT_C80963 hasExactSynonym "Ditiocarb Sodium" @default.
- NCIT_C80963 hasExactSynonym "Imuthiol" @default.
- NCIT_C80963 hasExactSynonym "Sodium Diethyldithiocarbamate" @default.
- NCIT_C80963 inSubset NCIT_C176424 @default.
- NCIT_C80963 inSubset NCIT_C63923 @default.
- NCIT_C80963 type Class @default.
- NCIT_C80963 isDefinedBy ncit.owl @default.
- NCIT_C80963 label "Ditiocarb Sodium" @default.
- NCIT_C80963 subClassOf NCIT_C1908 @default.
- NCIT_C80963 subClassOf NCIT_C1932 @default.
- NCIT_C80963 subClassOf NCIT_C360 @default.
- NCIT_C80963 subClassOf NCIT_C80963 @default.