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- NCIT_C81335 IAO_0000115 "A long-acting, small polar angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Libenzapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Libenzapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow." @default.
- NCIT_C81335 NCIT_NHC0 "C81335" @default.
- NCIT_C81335 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C81335 NCIT_P108 "Libenzapril" @default.
- NCIT_C81335 NCIT_P207 "C0055225" @default.
- NCIT_C81335 NCIT_P210 "97878-35-8" @default.
- NCIT_C81335 NCIT_P319 "QD8496WWYK" @default.
- NCIT_C81335 NCIT_P322 "FDA" @default.
- NCIT_C81335 NCIT_P350 "C18H25N3O5" @default.
- NCIT_C81335 NCIT_P366 "Libenzapril" @default.
- NCIT_C81335 normalizedInformationContent "100" @default.
- NCIT_C81335 referenceCount "1" @default.
- NCIT_C81335 hasExactSynonym "LIBENZAPRIL" @default.
- NCIT_C81335 hasExactSynonym "Libenzapril" @default.
- NCIT_C81335 inSubset NCIT_C63923 @default.
- NCIT_C81335 type Class @default.
- NCIT_C81335 isDefinedBy ncit.owl @default.
- NCIT_C81335 label "Libenzapril" @default.
- NCIT_C81335 subClassOf NCIT_C1908 @default.
- NCIT_C81335 subClassOf NCIT_C1909 @default.
- NCIT_C81335 subClassOf NCIT_C247 @default.
- NCIT_C81335 subClassOf NCIT_C270 @default.
- NCIT_C81335 subClassOf NCIT_C471 @default.
- NCIT_C81335 subClassOf NCIT_C78274 @default.
- NCIT_C81335 subClassOf NCIT_C783 @default.
- NCIT_C81335 subClassOf NCIT_C81335 @default.