Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C81539> ?p ?o ?g. }
Showing items 1 to 24 of
24
with 100 items per page.
- NCIT_C81539 IAO_0000115 "A thyroid hormone receptor isoform beta-1 liver-selective analog with antilipidemic and antiatherosclerotic activity. In animal models sobetirome reduced serum lipids, decreased cholesterol levels, and stimulated steps of reverse cholesterol transport, which promotes the reverse transport of cholesterol from atherogenic macrophages back to the liver for excretion. In humans, sobetirome lowered plasma LDL cholesterol and reduced plasma triglycerides, while its liver-selective activity helped avoid the side effects seen with many other thyromimetic agents." @default.
- NCIT_C81539 NCIT_NHC0 "C81539" @default.
- NCIT_C81539 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C81539 NCIT_P108 "Sobetirome" @default.
- NCIT_C81539 NCIT_P207 "C1135764" @default.
- NCIT_C81539 NCIT_P210 "211110-63-3" @default.
- NCIT_C81539 NCIT_P319 "XQ31741E9Q" @default.
- NCIT_C81539 NCIT_P322 "FDA" @default.
- NCIT_C81539 NCIT_P350 "C20H24O4" @default.
- NCIT_C81539 NCIT_P366 "Sobetirome" @default.
- NCIT_C81539 normalizedInformationContent "100" @default.
- NCIT_C81539 referenceCount "1" @default.
- NCIT_C81539 hasExactSynonym "GC-1" @default.
- NCIT_C81539 hasExactSynonym "SOBETIROME" @default.
- NCIT_C81539 hasExactSynonym "Sobetirome" @default.
- NCIT_C81539 inSubset NCIT_C63923 @default.
- NCIT_C81539 type Class @default.
- NCIT_C81539 isDefinedBy ncit.owl @default.
- NCIT_C81539 label "Sobetirome" @default.
- NCIT_C81539 subClassOf NCIT_C1908 @default.
- NCIT_C81539 subClassOf NCIT_C1909 @default.
- NCIT_C81539 subClassOf NCIT_C29703 @default.
- NCIT_C81539 subClassOf NCIT_C78276 @default.
- NCIT_C81539 subClassOf NCIT_C81539 @default.