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- NCIT_C81571 IAO_0000115 "The hydrochloride salt form of prasugrel, an orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration, the active metabolite of prasugrel targets and irreversibly binds to the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time." @default.
- NCIT_C81571 NCIT_A6 NCIT_C81566 @default.
- NCIT_C81571 NCIT_NHC0 "C81571" @default.
- NCIT_C81571 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C81571 NCIT_P108 "Prasugrel Hydrochloride" @default.
- NCIT_C81571 NCIT_P207 "C2683417" @default.
- NCIT_C81571 NCIT_P210 "389574-19-0" @default.
- NCIT_C81571 NCIT_P319 "G89JQ59I13" @default.
- NCIT_C81571 NCIT_P322 "FDA" @default.
- NCIT_C81571 NCIT_P350 "C20H20FNO3S.HCl" @default.
- NCIT_C81571 NCIT_P366 "Prasugrel_Hydrochloride" @default.
- NCIT_C81571 normalizedInformationContent "100" @default.
- NCIT_C81571 referenceCount "1" @default.
- NCIT_C81571 hasExactSynonym "Effient" @default.
- NCIT_C81571 hasExactSynonym "Efient" @default.
- NCIT_C81571 hasExactSynonym "PRASUGREL HYDROCHLORIDE" @default.
- NCIT_C81571 hasExactSynonym "Prasugrel Hydrochloride" @default.
- NCIT_C81571 inSubset NCIT_C173381 @default.
- NCIT_C81571 inSubset NCIT_C173383 @default.
- NCIT_C81571 inSubset NCIT_C63923 @default.
- NCIT_C81571 type Class @default.
- NCIT_C81571 isDefinedBy ncit.owl @default.
- NCIT_C81571 label "Prasugrel Hydrochloride" @default.
- NCIT_C81571 subClassOf NCIT_C1327 @default.
- NCIT_C81571 subClassOf NCIT_C1908 @default.
- NCIT_C81571 subClassOf NCIT_C190801 @default.
- NCIT_C81571 subClassOf NCIT_C1909 @default.
- NCIT_C81571 subClassOf NCIT_C78275 @default.
- NCIT_C81571 subClassOf NCIT_C80483 @default.
- NCIT_C81571 subClassOf NCIT_C81571 @default.