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- NCIT_C82348 IAO_0000115 "A humanized monovalent monoclonal antibody directed against the hepatocyte growth factor receptor (c-Met) with potential antineoplastic activity. Anti-MET monoclonal antibody MetMAb binds to the extracellular domain of c-Met, preventing the binding of its ligand, hepatocyte growth factor (HGF); the activation of the c-Met signaling pathway is thus inhibited, which may result in cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase, is overexpressed on the cell surfaces of a variety of cancer cell types and may play a key role in their proliferation, invasion and survival." @default.
- NCIT_C82348 NCIT_A32 NCIT_C1909 @default.
- NCIT_C82348 NCIT_NHC0 "C82348" @default.
- NCIT_C82348 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C82348 NCIT_P107 "Onartuzumab" @default.
- NCIT_C82348 NCIT_P108 "Onartuzumab" @default.
- NCIT_C82348 NCIT_P207 "C2826110" @default.
- NCIT_C82348 NCIT_P210 "1133766-06-9" @default.
- NCIT_C82348 NCIT_P319 "MS1J9720WC" @default.
- NCIT_C82348 NCIT_P322 "CTRP" @default.
- NCIT_C82348 NCIT_P322 "FDA" @default.
- NCIT_C82348 NCIT_P322 "GDC" @default.
- NCIT_C82348 NCIT_P329 "639516" @default.
- NCIT_C82348 NCIT_P330 "639516" @default.
- NCIT_C82348 NCIT_P366 "Anti-MET_Monoclonal_Antibody_MetMAb" @default.
- NCIT_C82348 NCIT_P375 "Onartuzumab" @default.
- NCIT_C82348 NCIT_P399 "639516" @default.
- NCIT_C82348 NCIT_R124 NCIT_C17710 @default.
- NCIT_C82348 NCIT_R124 NCIT_C17828 @default.
- NCIT_C82348 NCIT_R124 NCIT_C18219 @default.
- NCIT_C82348 NCIT_R124 NCIT_C19986 @default.
- NCIT_C82348 NCIT_R124 NCIT_C40474 @default.
- NCIT_C82348 normalizedInformationContent "100" @default.
- NCIT_C82348 referenceCount "1" @default.
- NCIT_C82348 hasExactSynonym "Anti-MET Monoclonal Antibody MetMAb" @default.
- NCIT_C82348 hasExactSynonym "MetMAb" @default.
- NCIT_C82348 hasExactSynonym "OA-5D5" @default.
- NCIT_C82348 hasExactSynonym "ONARTUZUMAB" @default.
- NCIT_C82348 hasExactSynonym "Onartuzumab" @default.
- NCIT_C82348 hasExactSynonym "PRO 143966" @default.
- NCIT_C82348 hasExactSynonym "RO5490258" @default.
- NCIT_C82348 inSubset NCIT_C116977 @default.
- NCIT_C82348 inSubset NCIT_C116978 @default.
- NCIT_C82348 inSubset NCIT_C128784 @default.
- NCIT_C82348 inSubset NCIT_C157711 @default.
- NCIT_C82348 inSubset NCIT_C157712 @default.
- NCIT_C82348 inSubset NCIT_C176424 @default.
- NCIT_C82348 inSubset NCIT_C177537 @default.
- NCIT_C82348 inSubset NCIT_C63923 @default.
- NCIT_C82348 type Class @default.
- NCIT_C82348 isDefinedBy ncit.owl @default.
- NCIT_C82348 label "Onartuzumab" @default.
- NCIT_C82348 subClassOf NCIT_C129821 @default.
- NCIT_C82348 subClassOf NCIT_C129822 @default.
- NCIT_C82348 subClassOf NCIT_C163758 @default.
- NCIT_C82348 subClassOf NCIT_C164000 @default.
- NCIT_C82348 subClassOf NCIT_C164001 @default.
- NCIT_C82348 subClassOf NCIT_C1908 @default.
- NCIT_C82348 subClassOf NCIT_C1909 @default.
- NCIT_C82348 subClassOf NCIT_C20401 @default.
- NCIT_C82348 subClassOf NCIT_C274 @default.
- NCIT_C82348 subClassOf NCIT_C307 @default.
- NCIT_C82348 subClassOf NCIT_C308 @default.
- NCIT_C82348 subClassOf NCIT_C82348 @default.