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- NCIT_C82357 IAO_0000115 "An orally bioavailable leucine enriched essential amino acid dietary supplement with potential anti-cachexia activity. Leucine-enhanced essential amino acid nutritional supplement may stimulate the mammalian target of rapamycin (mTOR) signaling pathway, which may promote protein synthesis in muscle cells. Although the exact mechanism by which leucine and other essential amino acids stimulate mTOR has yet to be fully elucidated, leucine may stimulate mTOR by inhibiting adenosine monophosphate protein kinase (AMPK), which negatively controls mTOR signaling." @default.
- NCIT_C82357 NCIT_NHC0 "C82357" @default.
- NCIT_C82357 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C82357 NCIT_P108 "Leucine-Enhanced Essential Amino Acid Dietary Supplement" @default.
- NCIT_C82357 NCIT_P208 "CL408637" @default.
- NCIT_C82357 NCIT_P329 "640231" @default.
- NCIT_C82357 NCIT_P330 "640231" @default.
- NCIT_C82357 NCIT_P366 "Leucine-Enhanced_Essential_Amino_Acid_Dietary_Supplement" @default.
- NCIT_C82357 NCIT_P399 "640231" @default.
- NCIT_C82357 normalizedInformationContent "100" @default.
- NCIT_C82357 referenceCount "1" @default.
- NCIT_C82357 hasExactSynonym "Leucine-Enhanced Essential Amino Acid Dietary Supplement" @default.
- NCIT_C82357 hasExactSynonym "Leucine-Enhanced Essential Amino Acids" @default.
- NCIT_C82357 inSubset NCIT_C176424 @default.
- NCIT_C82357 type Class @default.
- NCIT_C82357 isDefinedBy ncit.owl @default.
- NCIT_C82357 label "Leucine-Enhanced Essential Amino Acid Dietary Supplement" @default.
- NCIT_C82357 subClassOf NCIT_C1505 @default.
- NCIT_C82357 subClassOf NCIT_C1908 @default.
- NCIT_C82357 subClassOf NCIT_C82357 @default.