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- NCIT_C82371 IAO_0000115 "A whole, heat-killed, recombinant Saccharomyces cerevisiae yeast-based vaccine genetically altered to express the carcinoembryonic antigen (CEA) peptide 610D with potential immunostimulating and antineoplastic activities. Upon administration, recombinant Saccharomyces cerevisia-CEA(610D) vaccine GI-6207 may stimulate a host cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells, which may result in tumor cell lysis. CEA, a tumor associated antigen, is overexpressed on a wide variety of human cancer cells including colorectal, gastric, lung, breast and pancreatic cancer cells. CEA 610D encodes for 9 amino acids (605-613) in which aspartate is substituted for asparagine at position 610 (610D) in order to strengthen the induction of the CTL response against CEA-expressing tumor cells." @default.
- NCIT_C82371 NCIT_A32 NCIT_C1909 @default.
- NCIT_C82371 NCIT_A7 NCIT_C16384 @default.
- NCIT_C82371 NCIT_NHC0 "C82371" @default.
- NCIT_C82371 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C82371 NCIT_P107 "Recombinant Saccharomyces Cerevisia-CEA(610D)-Expressing Vaccine GI-6207" @default.
- NCIT_C82371 NCIT_P108 "Recombinant Saccharomyces Cerevisia-CEA(610D)-Expressing Vaccine GI-6207" @default.
- NCIT_C82371 NCIT_P207 "C2830061" @default.
- NCIT_C82371 NCIT_P319 "FIJ3OLQ3N8" @default.
- NCIT_C82371 NCIT_P322 "CTRP" @default.
- NCIT_C82371 NCIT_P322 "FDA" @default.
- NCIT_C82371 NCIT_P322 "GDC" @default.
- NCIT_C82371 NCIT_P329 "641167" @default.
- NCIT_C82371 NCIT_P330 "641167" @default.
- NCIT_C82371 NCIT_P366 "Recombinant_Saccharomyces_Cerevisia-CEA_610D_Expressing_Vaccine_GI-6207" @default.
- NCIT_C82371 NCIT_P375 "Recombinant Saccharomyces Cerevisia-CEA(610D)-Expressing Vaccine GI-6207" @default.
- NCIT_C82371 NCIT_P399 "641167" @default.
- NCIT_C82371 normalizedInformationContent "100" @default.
- NCIT_C82371 referenceCount "1" @default.
- NCIT_C82371 hasExactSynonym "GI-6207" @default.
- NCIT_C82371 hasExactSynonym "Recombinant Saccharomyces Cerevisia-CEA(610D)-Expressing Vaccine GI-6207" @default.
- NCIT_C82371 inSubset NCIT_C116977 @default.
- NCIT_C82371 inSubset NCIT_C116978 @default.
- NCIT_C82371 inSubset NCIT_C128784 @default.
- NCIT_C82371 inSubset NCIT_C157711 @default.
- NCIT_C82371 inSubset NCIT_C157712 @default.
- NCIT_C82371 inSubset NCIT_C176424 @default.
- NCIT_C82371 inSubset NCIT_C177537 @default.
- NCIT_C82371 inSubset NCIT_C63923 @default.
- NCIT_C82371 type Class @default.
- NCIT_C82371 isDefinedBy ncit.owl @default.
- NCIT_C82371 label "Recombinant Saccharomyces Cerevisia-CEA(610D)-Expressing Vaccine GI-6207" @default.
- NCIT_C82371 subClassOf NCIT_C129820 @default.
- NCIT_C82371 subClassOf NCIT_C1663 @default.
- NCIT_C82371 subClassOf NCIT_C1908 @default.
- NCIT_C82371 subClassOf NCIT_C1909 @default.
- NCIT_C82371 subClassOf NCIT_C274 @default.
- NCIT_C82371 subClassOf NCIT_C307 @default.
- NCIT_C82371 subClassOf NCIT_C308 @default.
- NCIT_C82371 subClassOf NCIT_C82371 @default.
- NCIT_C82371 subClassOf NCIT_C923 @default.