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- NCIT_C82411 IAO_0000115 "A fusion protein consisting of a mouse-human chimeric antibody directed against DNA released by necrotic tumor cells fused to two molecules of a genetically modified human interleukin-2 (IL-2) with potential antineoplastic activity. Upon administration, the antibody moiety of immunocytokine NHS-IL2-LT binds to DNA released by necrotic tumor cells located primarily at the core of necrotic solid tumors, delivering the IL-2 moiety. In turn, the IL-2 moiety of this agent activates the immune system to mount a cytotoxic T lymphocyte response against nearby tumor cells." @default.
- NCIT_C82411 NCIT_A32 NCIT_C1909 @default.
- NCIT_C82411 NCIT_NHC0 "C82411" @default.
- NCIT_C82411 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C82411 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C82411 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C82411 NCIT_P107 "Interleukin-2 Fusion Protein MSB0010445" @default.
- NCIT_C82411 NCIT_P108 "Immunocytokine NHS-IL2-LT" @default.
- NCIT_C82411 NCIT_P207 "C2830085" @default.
- NCIT_C82411 NCIT_P210 "1223034-72-7" @default.
- NCIT_C82411 NCIT_P319 "EI74F49ZLJ" @default.
- NCIT_C82411 NCIT_P322 "CTRP" @default.
- NCIT_C82411 NCIT_P322 "FDA" @default.
- NCIT_C82411 NCIT_P322 "GDC" @default.
- NCIT_C82411 NCIT_P329 "641919" @default.
- NCIT_C82411 NCIT_P330 "641919" @default.
- NCIT_C82411 NCIT_P366 "Selectikine" @default.
- NCIT_C82411 NCIT_P375 "Immunocytokine NHS-IL2-LT" @default.
- NCIT_C82411 NCIT_P399 "641919" @default.
- NCIT_C82411 NCIT_R124 NCIT_C17710 @default.
- NCIT_C82411 NCIT_R124 NCIT_C17828 @default.
- NCIT_C82411 NCIT_R124 NCIT_C18219 @default.
- NCIT_C82411 NCIT_R124 NCIT_C18992 @default.
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- NCIT_C82411 NCIT_R125 NCIT_C17937 @default.
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- NCIT_C82411 NCIT_R125 NCIT_C19053 @default.
- NCIT_C82411 NCIT_R125 NCIT_C21124 @default.
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- NCIT_C82411 NCIT_R125 NCIT_C40833 @default.
- NCIT_C82411 NCIT_R125 NCIT_C40912 @default.
- NCIT_C82411 NCIT_R72 NCIT_C104083 @default.
- NCIT_C82411 NCIT_R72 NCIT_C12219 @default.
- NCIT_C82411 NCIT_R72 NCIT_C12476 @default.
- NCIT_C82411 NCIT_R72 NCIT_C12508 @default.
- NCIT_C82411 NCIT_R72 NCIT_C12535 @default.
- NCIT_C82411 NCIT_R72 NCIT_C12542 @default.
- NCIT_C82411 NCIT_R72 NCIT_C12543 @default.
- NCIT_C82411 NCIT_R72 NCIT_C21599 @default.
- NCIT_C82411 NCIT_R72 NCIT_C32725 @default.
- NCIT_C82411 NCIT_R72 NCIT_C33061 @default.
- NCIT_C82411 NCIT_R72 NCIT_C38434 @default.
- NCIT_C82411 NCIT_R72 NCIT_C38439 @default.
- NCIT_C82411 NCIT_R72 NCIT_C39567 @default.
- NCIT_C82411 NCIT_R72 NCIT_C39568 @default.
- NCIT_C82411 normalizedInformationContent "100" @default.
- NCIT_C82411 referenceCount "1" @default.
- NCIT_C82411 hasExactSynonym "Ch.14.18-IL2" @default.
- NCIT_C82411 hasExactSynonym "EMD 521873" @default.
- NCIT_C82411 hasExactSynonym "Immunocytokine NHS-IL2-LT" @default.
- NCIT_C82411 hasExactSynonym "Interleukin-2 Fusion Protein MSB0010445" @default.
- NCIT_C82411 hasExactSynonym "MSB0010445" @default.
- NCIT_C82411 hasExactSynonym "NHS-IL2" @default.
- NCIT_C82411 hasExactSynonym "SELECTIKINE" @default.
- NCIT_C82411 hasExactSynonym "Selectikine" @default.
- NCIT_C82411 inSubset NCIT_C116977 @default.
- NCIT_C82411 inSubset NCIT_C116978 @default.
- NCIT_C82411 inSubset NCIT_C128784 @default.
- NCIT_C82411 inSubset NCIT_C157711 @default.
- NCIT_C82411 inSubset NCIT_C157712 @default.
- NCIT_C82411 inSubset NCIT_C176424 @default.
- NCIT_C82411 inSubset NCIT_C177537 @default.
- NCIT_C82411 inSubset NCIT_C63923 @default.
- NCIT_C82411 type Class @default.
- NCIT_C82411 isDefinedBy ncit.owl @default.
- NCIT_C82411 label "Immunocytokine NHS-IL2-LT" @default.
- NCIT_C82411 subClassOf B1da09c05dd0a8c161a2271fd9ee974d7 @default.
- NCIT_C82411 subClassOf B5a7dcfd5990d4f3e8940a8007de80480 @default.
- NCIT_C82411 subClassOf B6e1663c1338afa36f3454feef7a1986d @default.
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- NCIT_C82411 subClassOf NCIT_C1512 @default.
- NCIT_C82411 subClassOf NCIT_C1908 @default.
- NCIT_C82411 subClassOf NCIT_C1909 @default.
- NCIT_C82411 subClassOf NCIT_C307 @default.
- NCIT_C82411 subClassOf NCIT_C308 @default.
- NCIT_C82411 subClassOf NCIT_C82411 @default.