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- NCIT_C82414 IAO_0000115 "A radioimmunoconjugate consisting of the humanized monoclonal antibody lintuzumab conjugated to the alpha-emitting radioisotope actinium Ac 225 with potential antineoplastic activity. The monoclonal antibody moiety of actinium Ac 225 lintuzumab specifically binds to the cell surface antigen CD33 antigen, delivering a cytotoxic dose of alpha radiation to cells expressing CD33. CD33 is a cell surface antigen expressed on normal non-pluripotent hematopoietic stem cells and overexpressed on myeloid leukemia cells." @default.
- NCIT_C82414 NCIT_A32 NCIT_C1909 @default.
- NCIT_C82414 NCIT_NHC0 "C82414" @default.
- NCIT_C82414 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C82414 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C82414 NCIT_P108 "Actinium Ac 225 Lintuzumab" @default.
- NCIT_C82414 NCIT_P208 "CL408677" @default.
- NCIT_C82414 NCIT_P210 "2209911-94-2" @default.
- NCIT_C82414 NCIT_P319 "V860J30J9N" @default.
- NCIT_C82414 NCIT_P322 "FDA" @default.
- NCIT_C82414 NCIT_P322 "GDC" @default.
- NCIT_C82414 NCIT_P329 "637163" @default.
- NCIT_C82414 NCIT_P330 "637163" @default.
- NCIT_C82414 NCIT_P366 "Actinium_Ac_225_Lintuzumab" @default.
- NCIT_C82414 NCIT_P375 "Actinium Ac 225 Lintuzumab" @default.
- NCIT_C82414 NCIT_P399 "637163" @default.
- NCIT_C82414 normalizedInformationContent "100" @default.
- NCIT_C82414 referenceCount "1" @default.
- NCIT_C82414 hasExactSynonym "225Ac-HuM195" @default.
- NCIT_C82414 hasExactSynonym "Actimab-A" @default.
- NCIT_C82414 hasExactSynonym "Actinium (225Ac) Lintuzumab Satetraxetan" @default.
- NCIT_C82414 hasExactSynonym "Actinium Ac 225 Lintuzumab" @default.
- NCIT_C82414 hasExactSynonym "Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195" @default.
- NCIT_C82414 hasExactSynonym "LINTUZUMAB SATETRAXETAN AC-225" @default.
- NCIT_C82414 hasExactSynonym "SGN-33 AC-225" @default.
- NCIT_C82414 inSubset NCIT_C128784 @default.
- NCIT_C82414 inSubset NCIT_C157711 @default.
- NCIT_C82414 inSubset NCIT_C157712 @default.
- NCIT_C82414 inSubset NCIT_C176424 @default.
- NCIT_C82414 inSubset NCIT_C177537 @default.
- NCIT_C82414 inSubset NCIT_C63923 @default.
- NCIT_C82414 type Class @default.
- NCIT_C82414 isDefinedBy ncit.owl @default.
- NCIT_C82414 label "Actinium Ac 225 Lintuzumab" @default.
- NCIT_C82414 subClassOf NCIT_C129819 @default.
- NCIT_C82414 subClassOf NCIT_C1446 @default.
- NCIT_C82414 subClassOf NCIT_C1511 @default.
- NCIT_C82414 subClassOf NCIT_C1512 @default.
- NCIT_C82414 subClassOf NCIT_C1908 @default.
- NCIT_C82414 subClassOf NCIT_C1909 @default.
- NCIT_C82414 subClassOf NCIT_C200225 @default.
- NCIT_C82414 subClassOf NCIT_C2124 @default.
- NCIT_C82414 subClassOf NCIT_C274 @default.
- NCIT_C82414 subClassOf NCIT_C307 @default.
- NCIT_C82414 subClassOf NCIT_C308 @default.
- NCIT_C82414 subClassOf NCIT_C82414 @default.