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- NCIT_C82654 IAO_0000115 "A prostate cancer vaccine containing mRNAs encoding prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), prostate stem cell antigen (PSCA) and six-transmembrane epithelial antigen of the prostate (STEAP), with potential antitumor activity. Upon administration, mRNA-derived prostate cancer vaccine CV9103 may stimulate the immune system to mount a cytotoxic T lymphocyte response (CTL) against PSA-, PSMA-, PSCA- and STEAP-expressing prostate tumor cells. The mRNA used in this vaccine is modified and formulated to have enhanced translational potency and adjuvant activities. PSA, PSMA, PSCA and STEAP may be upregulated in prostate cancer cells; their expression in prostate cancer has been correlated with disease progression." @default.
- NCIT_C82654 NCIT_A32 NCIT_C1909 @default.
- NCIT_C82654 NCIT_NHC0 "C82654" @default.
- NCIT_C82654 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C82654 NCIT_P108 "mRNA-Derived Prostate Cancer Vaccine CV9103" @default.
- NCIT_C82654 NCIT_P208 "CL388486" @default.
- NCIT_C82654 NCIT_P322 "GDC" @default.
- NCIT_C82654 NCIT_P329 "636121" @default.
- NCIT_C82654 NCIT_P330 "636121" @default.
- NCIT_C82654 NCIT_P366 "mRNA-Derived_Prostate_Cancer_Vaccine_CV9103" @default.
- NCIT_C82654 NCIT_P375 "mRNA-Derived Prostate Cancer Vaccine CV9103" @default.
- NCIT_C82654 NCIT_P399 "636121" @default.
- NCIT_C82654 normalizedInformationContent "100" @default.
- NCIT_C82654 referenceCount "1" @default.
- NCIT_C82654 hasExactSynonym "CV9103" @default.
- NCIT_C82654 hasExactSynonym "Messenger RNA-Derived Prostate Cancer Vaccine CV9103" @default.
- NCIT_C82654 hasExactSynonym "mRNA-Derived Prostate Cancer Vaccine CV9103" @default.
- NCIT_C82654 inSubset NCIT_C128784 @default.
- NCIT_C82654 inSubset NCIT_C157711 @default.
- NCIT_C82654 inSubset NCIT_C157712 @default.
- NCIT_C82654 inSubset NCIT_C176424 @default.
- NCIT_C82654 inSubset NCIT_C177537 @default.
- NCIT_C82654 type Class @default.
- NCIT_C82654 isDefinedBy ncit.owl @default.
- NCIT_C82654 label "mRNA-Derived Prostate Cancer Vaccine CV9103" @default.
- NCIT_C82654 subClassOf NCIT_C129820 @default.
- NCIT_C82654 subClassOf NCIT_C1663 @default.
- NCIT_C82654 subClassOf NCIT_C172787 @default.
- NCIT_C82654 subClassOf NCIT_C181141 @default.
- NCIT_C82654 subClassOf NCIT_C1908 @default.
- NCIT_C82654 subClassOf NCIT_C1909 @default.
- NCIT_C82654 subClassOf NCIT_C274 @default.
- NCIT_C82654 subClassOf NCIT_C307 @default.
- NCIT_C82654 subClassOf NCIT_C308 @default.
- NCIT_C82654 subClassOf NCIT_C82654 @default.
- NCIT_C82654 subClassOf NCIT_C923 @default.