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- NCIT_C827 IAO_0000115 "A methylated derivative of carmustine with antineoplastic activity. As an alkylating agent, semustine forms covalent linkages with nucleophilic centers in DNA, causing depurination, base-pair miscoding, strand scission, and DNA-DNA cross-linking, which may result in cytotoxicity. (NCI04)" @default.
- NCIT_C827 NCIT_A32 NCIT_C1909 @default.
- NCIT_C827 NCIT_NHC0 "C827" @default.
- NCIT_C827 NCIT_P106 "Organic Chemical" @default.
- NCIT_C827 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C827 NCIT_P108 "Semustine" @default.
- NCIT_C827 NCIT_P175 "95441" @default.
- NCIT_C827 NCIT_P207 "C0036637" @default.
- NCIT_C827 NCIT_P210 "13909-09-6" @default.
- NCIT_C827 NCIT_P319 "6YY7T1T567" @default.
- NCIT_C827 NCIT_P322 "FDA" @default.
- NCIT_C827 NCIT_P322 "GDC" @default.
- NCIT_C827 NCIT_P325 "An anticancer drug that belongs to the family of drugs called alkylating agents." @default.
- NCIT_C827 NCIT_P329 "43727" @default.
- NCIT_C827 NCIT_P330 "43727" @default.
- NCIT_C827 NCIT_P366 "Semustine" @default.
- NCIT_C827 NCIT_P375 "Semustine" @default.
- NCIT_C827 NCIT_P399 "43727" @default.
- NCIT_C827 normalizedInformationContent "83.027314241919257" @default.
- NCIT_C827 referenceCount "13" @default.
- NCIT_C827 hasExactSynonym "1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea" @default.
- NCIT_C827 hasExactSynonym "1-(2-Chloroethyl)-3-(Trans-4-Methylcyclohexane)-1-Nitrosourea" @default.
- NCIT_C827 hasExactSynonym "1-(2-Chloroethyl)-3-(trans-4-methylcyclohexane)-1-nitrosourea" @default.
- NCIT_C827 hasExactSynonym "1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea" @default.
- NCIT_C827 hasExactSynonym "Lomustine, Methyl" @default.
- NCIT_C827 hasExactSynonym "Lomustine, methyl" @default.
- NCIT_C827 hasExactSynonym "MCCNU" @default.
- NCIT_C827 hasExactSynonym "MeCCNU" @default.
- NCIT_C827 hasExactSynonym "Methyl CCNU" @default.
- NCIT_C827 hasExactSynonym "Methyl Lomustine" @default.
- NCIT_C827 hasExactSynonym "SEMUSTINE" @default.
- NCIT_C827 hasExactSynonym "Semustine" @default.
- NCIT_C827 hasExactSynonym "Urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, trans- (8CI)" @default.
- NCIT_C827 hasExactSynonym "Urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, trans- (9CI)" @default.
- NCIT_C827 hasExactSynonym "methyl-CCNU" @default.
- NCIT_C827 hasExactSynonym "semustine" @default.
- NCIT_C827 hasExactSynonym "trans-Methyl-CCNU" @default.
- NCIT_C827 hasExactSynonym "urea, 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-, trans- (8CI)" @default.
- NCIT_C827 hasExactSynonym "urea, N-(2-chloroethyl)-N'-(4-methylcyclohexyl)-N-nitroso-, trans- (9CI)" @default.
- NCIT_C827 inSubset NCIT_C128784 @default.
- NCIT_C827 inSubset NCIT_C157711 @default.
- NCIT_C827 inSubset NCIT_C157712 @default.
- NCIT_C827 inSubset NCIT_C176424 @default.
- NCIT_C827 inSubset NCIT_C177537 @default.
- NCIT_C827 inSubset NCIT_C63923 @default.
- NCIT_C827 type Class @default.
- NCIT_C827 isDefinedBy ncit.owl @default.
- NCIT_C827 label "Semustine" @default.
- NCIT_C827 subClassOf NCIT_C1590 @default.
- NCIT_C827 subClassOf NCIT_C186664 @default.
- NCIT_C827 subClassOf NCIT_C1908 @default.
- NCIT_C827 subClassOf NCIT_C1909 @default.
- NCIT_C827 subClassOf NCIT_C274 @default.
- NCIT_C827 subClassOf NCIT_C2842 @default.
- NCIT_C827 subClassOf NCIT_C699 @default.
- NCIT_C827 subClassOf NCIT_C827 @default.