Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C82854> ?p ?o ?g. }
- NCIT_C82854 IAO_0000115 "Prothrombin (622 aa, ~70 kDa) is encoded by the human F2 gene. This protein plays a role in both coagulation and proteolysis of fibrinogen." @default.
- NCIT_C82854 NCIT_NHC0 "C82854" @default.
- NCIT_C82854 NCIT_P100 "176930" @default.
- NCIT_C82854 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C82854 NCIT_P106 "Enzyme" @default.
- NCIT_C82854 NCIT_P107 "Prothrombin" @default.
- NCIT_C82854 NCIT_P108 "Prothrombin" @default.
- NCIT_C82854 NCIT_P208 "CL449006" @default.
- NCIT_C82854 NCIT_P322 "CTRP" @default.
- NCIT_C82854 NCIT_P366 "Prothrombin_Gene_Product" @default.
- NCIT_C82854 NCIT_P93 "P00734" @default.
- NCIT_C82854 NCIT_P98 "Prior to secretion, prothrombin is modified to have gamma-carboxyglutamyl residues, resulting from the carboxylation of glutamyl residues by vitamin K-dependent gamma-carboxylase. These modified residues are necessary for the calcium-dependent interaction with a negatively charged phospholipid surface, which is essential for the conversion of prothrombin to thrombin. (UniProt)" @default.
- NCIT_C82854 NCIT_P98 "Prothrombin activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. (UniProt)" @default.
- NCIT_C82854 NCIT_P98 "Prothrombin catalyzes the cleavage of Arg-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B. (UniProt)" @default.
- NCIT_C82854 NCIT_P98 "Prothrombin protein can be cleaved into the following 4 chains: activation peptide fragment 1, activation peptide fragment 2, thrombin light chain, thrombin heavy chain. (UniProt)" @default.
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- NCIT_C82854 normalizedInformationContent "100" @default.
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- NCIT_C82854 hasExactSynonym "Coagulation Factor II" @default.
- NCIT_C82854 hasExactSynonym "EC 3.4.21.5" @default.
- NCIT_C82854 hasExactSynonym "F2" @default.
- NCIT_C82854 hasExactSynonym "Factor II" @default.
- NCIT_C82854 hasExactSynonym "Prothrombin" @default.
- NCIT_C82854 inSubset NCIT_C116977 @default.
- NCIT_C82854 inSubset NCIT_C142799 @default.