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- NCIT_C83780 IAO_0000115 "A hydroxamic, non-amino acid derivative angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Idrapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Idrapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow." @default.
- NCIT_C83780 NCIT_NHC0 "C83780" @default.
- NCIT_C83780 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C83780 NCIT_P108 "Idrapril" @default.
- NCIT_C83780 NCIT_P207 "C0172867" @default.
- NCIT_C83780 NCIT_P210 "127420-24-0" @default.
- NCIT_C83780 NCIT_P319 "176P5C4QU8" @default.
- NCIT_C83780 NCIT_P322 "FDA" @default.
- NCIT_C83780 NCIT_P350 "C11H18N2O5" @default.
- NCIT_C83780 normalizedInformationContent "100" @default.
- NCIT_C83780 referenceCount "1" @default.
- NCIT_C83780 hasExactSynonym "IDRAPRIL" @default.
- NCIT_C83780 hasExactSynonym "Idrapril" @default.
- NCIT_C83780 inSubset NCIT_C63923 @default.
- NCIT_C83780 type Class @default.
- NCIT_C83780 isDefinedBy ncit.owl @default.
- NCIT_C83780 label "Idrapril" @default.
- NCIT_C83780 subClassOf NCIT_C1908 @default.
- NCIT_C83780 subClassOf NCIT_C1909 @default.
- NCIT_C83780 subClassOf NCIT_C247 @default.
- NCIT_C83780 subClassOf NCIT_C270 @default.
- NCIT_C83780 subClassOf NCIT_C471 @default.
- NCIT_C83780 subClassOf NCIT_C78274 @default.
- NCIT_C83780 subClassOf NCIT_C783 @default.
- NCIT_C83780 subClassOf NCIT_C83780 @default.