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- NCIT_C83818 IAO_0000115 "An analog of calcitriol and a vitamin D3 receptor (VDR) agonist, with potential antineoplastic activity. Upon administration, inecalcitol targets and binds to VDR. This activates VDR and VDR-mediated signal transduction pathways. This modulates the VDR-mediated expression of certain genes, including the expression of anti-cancer genes, enhances cellular differentiation, induces tumor cell apoptosis and inhibits tumor cell growth. VDR plays a central role in calcium homeostasis and in the growth of certain cancer cells." @default.
- NCIT_C83818 NCIT_A32 NCIT_C1909 @default.
- NCIT_C83818 NCIT_A7 NCIT_C17485 @default.
- NCIT_C83818 NCIT_NHC0 "C83818" @default.
- NCIT_C83818 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C83818 NCIT_P107 "Inecalcitol" @default.
- NCIT_C83818 NCIT_P108 "Inecalcitol" @default.
- NCIT_C83818 NCIT_P207 "C2827203" @default.
- NCIT_C83818 NCIT_P210 "163217-09-2" @default.
- NCIT_C83818 NCIT_P319 "05FZV98342" @default.
- NCIT_C83818 NCIT_P322 "CTRP" @default.
- NCIT_C83818 NCIT_P322 "FDA" @default.
- NCIT_C83818 NCIT_P322 "GDC" @default.
- NCIT_C83818 NCIT_P329 "782341" @default.
- NCIT_C83818 NCIT_P330 "782341" @default.
- NCIT_C83818 NCIT_P350 "C26H40O3" @default.
- NCIT_C83818 NCIT_P375 "Inecalcitol" @default.
- NCIT_C83818 NCIT_P399 "782341" @default.
- NCIT_C83818 normalizedInformationContent "100" @default.
- NCIT_C83818 referenceCount "1" @default.
- NCIT_C83818 hasExactSynonym "(7E)-19-Nor-9,10-seco-14beta-cholesta-5,7-dien-23-yne-1alpha,3beta,25-triol" @default.
- NCIT_C83818 hasExactSynonym "ICC" @default.
- NCIT_C83818 hasExactSynonym "INECALCITOL" @default.
- NCIT_C83818 hasExactSynonym "Inecalcitol" @default.
- NCIT_C83818 hasExactSynonym "TX 522" @default.
- NCIT_C83818 inSubset NCIT_C116977 @default.
- NCIT_C83818 inSubset NCIT_C116978 @default.
- NCIT_C83818 inSubset NCIT_C128784 @default.
- NCIT_C83818 inSubset NCIT_C157711 @default.
- NCIT_C83818 inSubset NCIT_C157712 @default.
- NCIT_C83818 inSubset NCIT_C176424 @default.
- NCIT_C83818 inSubset NCIT_C177537 @default.
- NCIT_C83818 inSubset NCIT_C63923 @default.
- NCIT_C83818 type Class @default.
- NCIT_C83818 isDefinedBy ncit.owl @default.
- NCIT_C83818 label "Inecalcitol" @default.
- NCIT_C83818 subClassOf NCIT_C1505 @default.
- NCIT_C83818 subClassOf NCIT_C1908 @default.
- NCIT_C83818 subClassOf NCIT_C39713 @default.
- NCIT_C83818 subClassOf NCIT_C83818 @default.