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- NCIT_C83819 IAO_0000115 "An orally bioavailable thiazolidinedione and an agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic activity. Efatutazone binds to and activates PPAR-gamma thus inducing cell differentiation and apoptosis, leading to a reduction in cellular proliferation. PPAR-gamma is a nuclear hormone receptor and a ligand-activated transcription factor that controls the expression of genes involved in macromolecule metabolism and cell differentiation, specifically adipocyte differentiation." @default.
- NCIT_C83819 NCIT_A32 NCIT_C1909 @default.
- NCIT_C83819 NCIT_NHC0 "C83819" @default.
- NCIT_C83819 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C83819 NCIT_P108 "Efatutazone" @default.
- NCIT_C83819 NCIT_P207 "C2827204" @default.
- NCIT_C83819 NCIT_P210 "223132-37-4" @default.
- NCIT_C83819 NCIT_P319 "M17ILL71MC" @default.
- NCIT_C83819 NCIT_P322 "FDA" @default.
- NCIT_C83819 NCIT_P322 "GDC" @default.
- NCIT_C83819 NCIT_P350 "C27H26N4O4S" @default.
- NCIT_C83819 NCIT_P375 "Efatutazone" @default.
- NCIT_C83819 normalizedInformationContent "100" @default.
- NCIT_C83819 referenceCount "1" @default.
- NCIT_C83819 hasExactSynonym "2,4-Thiazolidinedione, 5-((4-((6-(4-Amino-3,5-Dimethylphenoxy)-1-Methyl-1H-Benzimidazol-2-yl)Methoxy)Phenyl)Methyl)-" @default.
- NCIT_C83819 hasExactSynonym "EFATUTAZONE" @default.
- NCIT_C83819 hasExactSynonym "Efatutazone" @default.
- NCIT_C83819 hasExactSynonym "Inolitazone" @default.
- NCIT_C83819 hasExactSynonym "Rac-5-((4-((6-(4-Amino-3,5-Dimethylphenoxy)-1-Methyl-1H-Benzimidazol-2-yl)Methoxy)Phenyl)Methyl)-1,3-Thiazolidine-2,4-Dione" @default.
- NCIT_C83819 inSubset NCIT_C128784 @default.
- NCIT_C83819 inSubset NCIT_C157711 @default.
- NCIT_C83819 inSubset NCIT_C157712 @default.
- NCIT_C83819 inSubset NCIT_C177537 @default.
- NCIT_C83819 inSubset NCIT_C63923 @default.
- NCIT_C83819 type Class @default.
- NCIT_C83819 isDefinedBy ncit.owl @default.
- NCIT_C83819 label "Efatutazone" @default.
- NCIT_C83819 subClassOf NCIT_C1908 @default.
- NCIT_C83819 subClassOf NCIT_C1909 @default.
- NCIT_C83819 subClassOf NCIT_C1934 @default.
- NCIT_C83819 subClassOf NCIT_C2122 @default.
- NCIT_C83819 subClassOf NCIT_C274 @default.
- NCIT_C83819 subClassOf NCIT_C83819 @default.