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- NCIT_C83967 IAO_0000115 "A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, moexipril is hydrolyzed into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis." @default.
- NCIT_C83967 NCIT_A5 NCIT_C29267 @default.
- NCIT_C83967 NCIT_NHC0 "C83967" @default.
- NCIT_C83967 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C83967 NCIT_P108 "Moexipril" @default.
- NCIT_C83967 NCIT_P207 "C0066685" @default.
- NCIT_C83967 NCIT_P210 "103775-10-6" @default.
- NCIT_C83967 NCIT_P319 "WT87C52TJZ" @default.
- NCIT_C83967 NCIT_P322 "FDA" @default.
- NCIT_C83967 NCIT_P350 "C27H34N2O7" @default.
- NCIT_C83967 normalizedInformationContent "100" @default.
- NCIT_C83967 referenceCount "1" @default.
- NCIT_C83967 hasExactSynonym "MOEXIPRIL" @default.
- NCIT_C83967 hasExactSynonym "Moexipril" @default.
- NCIT_C83967 inSubset NCIT_C63923 @default.
- NCIT_C83967 type Class @default.
- NCIT_C83967 isDefinedBy ncit.owl @default.
- NCIT_C83967 label "Moexipril" @default.
- NCIT_C83967 subClassOf NCIT_C1908 @default.
- NCIT_C83967 subClassOf NCIT_C1909 @default.
- NCIT_C83967 subClassOf NCIT_C247 @default.
- NCIT_C83967 subClassOf NCIT_C270 @default.
- NCIT_C83967 subClassOf NCIT_C471 @default.
- NCIT_C83967 subClassOf NCIT_C78274 @default.
- NCIT_C83967 subClassOf NCIT_C783 @default.
- NCIT_C83967 subClassOf NCIT_C83967 @default.