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- NCIT_C84844 IAO_0000115 "A cancer vaccine containing four HLA-A*0201-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Vaccine peptide epitopes are derived from the tumor associated antigens (TAAs) tyrosinase-related protein 2 (TRP2), glycoprotein 100 (gp100), Ephrin receptor A2 (EphA2) and human epidermal growth factor receptor 2 (HER2). Upon administration, HLA-A*0201-restricted TRp2-gp100-EphA2-HER2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against TRP2-gp100-EphA2-HER2-expressing tumor cells, resulting in tumor cell lysis and decreased tumor cell proliferation. HLA-A*0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." @default.
- NCIT_C84844 NCIT_A7 NCIT_C17319 @default.
- NCIT_C84844 NCIT_A7 NCIT_C26156 @default.
- NCIT_C84844 NCIT_A7 NCIT_C2646 @default.
- NCIT_C84844 NCIT_A7 NCIT_C41037 @default.
- NCIT_C84844 NCIT_NHC0 "C84844" @default.
- NCIT_C84844 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C84844 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C84844 NCIT_P107 "HLA-A*0201-restricted TRP2-gp100-EphA2-HER2 Multipeptide Vaccine" @default.
- NCIT_C84844 NCIT_P108 "HLA-A*0201-restricted TRP2-gp100-EphA2-HER2 Multipeptide Vaccine" @default.
- NCIT_C84844 NCIT_P208 "CL412397" @default.
- NCIT_C84844 NCIT_P322 "CTRP" @default.
- NCIT_C84844 NCIT_P329 "650427" @default.
- NCIT_C84844 NCIT_P330 "650427" @default.
- NCIT_C84844 NCIT_P399 "650427" @default.
- NCIT_C84844 NCIT_R124 NCIT_C17828 @default.
- NCIT_C84844 NCIT_R124 NCIT_C17930 @default.
- NCIT_C84844 NCIT_R124 NCIT_C17937 @default.
- NCIT_C84844 NCIT_R124 NCIT_C18839 @default.
- NCIT_C84844 NCIT_R124 NCIT_C21124 @default.
- NCIT_C84844 NCIT_R124 NCIT_C45548 @default.
- NCIT_C84844 normalizedInformationContent "100" @default.
- NCIT_C84844 referenceCount "1" @default.
- NCIT_C84844 hasExactSynonym "HLA-A*0201-restricted TRP2-gp100-EphA2-HER2 Multipeptide Vaccine" @default.
- NCIT_C84844 inSubset NCIT_C116977 @default.
- NCIT_C84844 inSubset NCIT_C116978 @default.
- NCIT_C84844 inSubset NCIT_C128784 @default.
- NCIT_C84844 inSubset NCIT_C176424 @default.
- NCIT_C84844 type Class @default.
- NCIT_C84844 isDefinedBy ncit.owl @default.
- NCIT_C84844 label "HLA-A*0201-restricted TRP2-gp100-EphA2-HER2 Multipeptide Vaccine" @default.
- NCIT_C84844 subClassOf NCIT_C129820 @default.
- NCIT_C84844 subClassOf NCIT_C1663 @default.
- NCIT_C84844 subClassOf NCIT_C1752 @default.
- NCIT_C84844 subClassOf NCIT_C1908 @default.
- NCIT_C84844 subClassOf NCIT_C1909 @default.
- NCIT_C84844 subClassOf NCIT_C274 @default.
- NCIT_C84844 subClassOf NCIT_C307 @default.
- NCIT_C84844 subClassOf NCIT_C308 @default.
- NCIT_C84844 subClassOf NCIT_C84844 @default.
- NCIT_C84844 subClassOf NCIT_C923 @default.