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- NCIT_C84860 IAO_0000115 "A water-soluble, positively charged fusion protein consisting of a luteinizing hormone releasing hormone (LHRH) receptor-targeting ligand conjugated to the membrane-disrupting peptide CLIP 71 with membrane-disrupting and potential antineoplastic activities. The LHRH ligand moiety of onvitrelin ucalontide specifically binds to LHRH receptors, which are upregulated on a variety of human cancer cell types. Subsequently, the positively charged CLIP 71 moiety of this agent interacts with the negatively charged membrane on the cancer cell surface, which may result in cell membrane disruption and cell lysis." @default.
- NCIT_C84860 NCIT_A32 NCIT_C1909 @default.
- NCIT_C84860 NCIT_A7 NCIT_C38910 @default.
- NCIT_C84860 NCIT_NHC0 "C84860" @default.
- NCIT_C84860 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C84860 NCIT_P107 "Onvitrelin Ucalontide" @default.
- NCIT_C84860 NCIT_P108 "Onvitrelin Ucalontide" @default.
- NCIT_C84860 NCIT_P208 "CL412421" @default.
- NCIT_C84860 NCIT_P210 "1620643-19-7" @default.
- NCIT_C84860 NCIT_P319 "UF1EL37E41" @default.
- NCIT_C84860 NCIT_P322 "CTRP" @default.
- NCIT_C84860 NCIT_P322 "FDA" @default.
- NCIT_C84860 NCIT_P322 "GDC" @default.
- NCIT_C84860 NCIT_P329 "652192" @default.
- NCIT_C84860 NCIT_P330 "652192" @default.
- NCIT_C84860 NCIT_P375 "Membrane-Disrupting Peptide EP-100" @default.
- NCIT_C84860 NCIT_P399 "652192" @default.
- NCIT_C84860 normalizedInformationContent "100" @default.
- NCIT_C84860 referenceCount "1" @default.
- NCIT_C84860 hasExactSynonym "EP-100" @default.
- NCIT_C84860 hasExactSynonym "Membrane-Disrupting Peptide EP-100" @default.
- NCIT_C84860 hasExactSynonym "ONVITRELIN UCALONTIDE" @default.
- NCIT_C84860 hasExactSynonym "Onvitrelin Ucalontide" @default.
- NCIT_C84860 inSubset NCIT_C116977 @default.
- NCIT_C84860 inSubset NCIT_C116978 @default.
- NCIT_C84860 inSubset NCIT_C128784 @default.
- NCIT_C84860 inSubset NCIT_C157711 @default.
- NCIT_C84860 inSubset NCIT_C157712 @default.
- NCIT_C84860 inSubset NCIT_C176424 @default.
- NCIT_C84860 inSubset NCIT_C177537 @default.
- NCIT_C84860 inSubset NCIT_C63923 @default.
- NCIT_C84860 type Class @default.
- NCIT_C84860 isDefinedBy ncit.owl @default.
- NCIT_C84860 label "Onvitrelin Ucalontide" @default.
- NCIT_C84860 subClassOf NCIT_C1512 @default.
- NCIT_C84860 subClassOf NCIT_C1908 @default.
- NCIT_C84860 subClassOf NCIT_C1909 @default.
- NCIT_C84860 subClassOf NCIT_C307 @default.
- NCIT_C84860 subClassOf NCIT_C308 @default.
- NCIT_C84860 subClassOf NCIT_C84860 @default.