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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C870> ?p ?o ?g. }

• NCIT_C870 IAO_0000115 "A synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis." @default.
• NCIT_C870 NCIT_A32 NCIT_C1909 @default.
• NCIT_C870 NCIT_A7 NCIT_C20450 @default.
• NCIT_C870 NCIT_A7 NCIT_C20535 @default.
• NCIT_C870 NCIT_NHC0 "C870" @default.
• NCIT_C870 NCIT_P106 "Organic Chemical" @default.
• NCIT_C870 NCIT_P106 "Pharmacologic Substance" @default.
• NCIT_C870 NCIT_P107 "Thalidomide" @default.
• NCIT_C870 NCIT_P108 "Thalidomide" @default.
• NCIT_C870 NCIT_P175 "66847" @default.
• NCIT_C870 NCIT_P207 "C0039736" @default.
• NCIT_C870 NCIT_P210 "50-35-1" @default.
• NCIT_C870 NCIT_P302 "Aphthous stomatitis; Crohns disease; cutaneous manifestations of erythema nodosum leprosum; GVHD; HIV-associated wasting syndrome; Karposi sarcoma; lepromatous leprosy; multiple myeloma; mycobacterium tuberculosis and nontuberculosis; primary brain tumors" @default.
• NCIT_C870 NCIT_P319 "4Z8R6ORS6L" @default.
• NCIT_C870 NCIT_P322 "CTRP" @default.
• NCIT_C870 NCIT_P322 "FDA" @default.
• NCIT_C870 NCIT_P322 "GDC" @default.
• NCIT_C870 NCIT_P325 "A drug that is used to treat multiple myeloma in patients who have just been diagnosed, and a painful skin disease related to leprosy. It is also being studied in the treatment of other types of cancer. Thalomid belongs to the family of drugs called angiogenesis inhibitors." @default.
• NCIT_C870 NCIT_P329 "42332" @default.
• NCIT_C870 NCIT_P330 "42332" @default.
• NCIT_C870 NCIT_P350 "C13H10N2O4" @default.
• NCIT_C870 NCIT_P366 "Thalidomide" @default.
• NCIT_C870 NCIT_P368 "CHEBI:9513" @default.
• NCIT_C870 NCIT_P375 "Thalidomide" @default.
• NCIT_C870 NCIT_P399 "42332" @default.
• NCIT_C870 NCIT_R124 NCIT_C17710 @default.
• NCIT_C870 NCIT_R124 NCIT_C17828 @default.
• NCIT_C870 NCIT_R124 NCIT_C19986 @default.
• NCIT_C870 NCIT_R124 NCIT_C40551 @default.
• NCIT_C870 NCIT_R125 NCIT_C16422 @default.
• NCIT_C870 NCIT_R125 NCIT_C16544 @default.
• NCIT_C870 NCIT_R125 NCIT_C17710 @default.
• NCIT_C870 NCIT_R125 NCIT_C17828 @default.
• NCIT_C870 NCIT_R125 NCIT_C17932 @default.
• NCIT_C870 NCIT_R125 NCIT_C19950 @default.
• NCIT_C870 NCIT_R125 NCIT_C20480 @default.
• NCIT_C870 NCIT_R125 NCIT_C21079 @default.
• NCIT_C870 NCIT_R125 NCIT_C21124 @default.
• NCIT_C870 NCIT_R125 NCIT_C21128 @default.
• NCIT_C870 NCIT_R125 NCIT_C21147 @default.
• NCIT_C870 NCIT_R125 NCIT_C26044 @default.
• NCIT_C870 NCIT_R125 NCIT_C28486 @default.
• NCIT_C870 NCIT_R125 NCIT_C28498 @default.
• NCIT_C870 NCIT_R125 NCIT_C40752 @default.
• NCIT_C870 NCIT_R125 NCIT_C40792 @default.
• NCIT_C870 NCIT_R125 NCIT_C40806 @default.
• NCIT_C870 NCIT_R125 NCIT_C41517 @default.
• NCIT_C870 NCIT_R72 NCIT_C12219 @default.
• NCIT_C870 NCIT_R72 NCIT_C12508 @default.
• NCIT_C870 NCIT_R72 NCIT_C12519 @default.
• NCIT_C870 NCIT_R72 NCIT_C12529 @default.
• NCIT_C870 NCIT_R72 NCIT_C12547 @default.
• NCIT_C870 NCIT_R72 NCIT_C12555 @default.
• NCIT_C870 NCIT_R72 NCIT_C12865 @default.
• NCIT_C870 NCIT_R72 NCIT_C21599 @default.
• NCIT_C870 NCIT_R72 NCIT_C32725 @default.
• NCIT_C870 normalizedInformationContent "75.111529024455209" @default.
• NCIT_C870 referenceCount "43" @default.
• NCIT_C870 hasExactSynonym "(+)-Thalidomide" @default.
• NCIT_C870 hasExactSynonym "(-)-Thalidomide" @default.
• NCIT_C870 hasExactSynonym ".alpha.-Phthalimidoglutarimide" @default.
• NCIT_C870 hasExactSynonym "2, 6-Dioxo-3-phthalimidopiperidine" @default.
• NCIT_C870 hasExactSynonym "2,6-Dioxo-3-phthalimidopiperidine" @default.
• NCIT_C870 hasExactSynonym "2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione" @default.
• NCIT_C870 hasExactSynonym "3-Phthalimidoglutarimide" @default.
• NCIT_C870 hasExactSynonym "Alpha-Phthalimidoglutarimide" @default.
• NCIT_C870 hasExactSynonym "Contergan" @default.
• NCIT_C870 hasExactSynonym "Distaval" @default.
• NCIT_C870 hasExactSynonym "Kevadon" @default.
• NCIT_C870 hasExactSynonym "N-(2,6-Dioxo-3-piperidyl)phthalimide" @default.
• NCIT_C870 hasExactSynonym "N-Phthaloylglutamimide" @default.
• NCIT_C870 hasExactSynonym "N-Phthalylglutamic Acid Imide" @default.
• NCIT_C870 hasExactSynonym "N-Phthalylglutamic acid imide" @default.
• NCIT_C870 hasExactSynonym "Neurosedyn" @default.
• NCIT_C870 hasExactSynonym "Pantosediv" @default.
• NCIT_C870 hasExactSynonym "Phthalimide, N-(2, 6-dioxo-3-piperidyl)-, (+)-" @default.
• NCIT_C870 hasExactSynonym "Phthalimide, N-(2, 6-dioxo-3-piperidyl)-, (-)-" @default.
• NCIT_C870 hasExactSynonym "Sedalis" @default.
• NCIT_C870 hasExactSynonym "Sedoval K-17" @default.
• NCIT_C870 hasExactSynonym "Sedoval K17" @default.
• NCIT_C870 hasExactSynonym "Softenon" @default.
• NCIT_C870 hasExactSynonym "Synovir" @default.
• NCIT_C870 hasExactSynonym "THALIDOMIDE" @default.
• NCIT_C870 hasExactSynonym "Talimol" @default.
• NCIT_C870 hasExactSynonym "Thalidomide" @default.
• NCIT_C870 hasExactSynonym "Thalomid" @default.
• NCIT_C870 hasExactSynonym "thalidomide" @default.
• NCIT_C870 inSubset NCIT_C116977 @default.
• NCIT_C870 inSubset NCIT_C116978 @default.
• NCIT_C870 inSubset NCIT_C128784 @default.
• NCIT_C870 inSubset NCIT_C157711 @default.
• NCIT_C870 inSubset NCIT_C157712 @default.
• NCIT_C870 inSubset NCIT_C173381 @default.
• NCIT_C870 inSubset NCIT_C173383 @default.
• NCIT_C870 inSubset NCIT_C176424 @default.
• NCIT_C870 inSubset NCIT_C177537 @default.
• NCIT_C870 inSubset NCIT_C63923 @default.
• NCIT_C870 type Class @default.
• NCIT_C870 isDefinedBy ncit.owl @default.
• NCIT_C870 label "Thalidomide" @default.

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