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- NCIT_C87060 IAO_0000115 "A combination formulation containing the hydrochloride salt form of the benzodiazepine chlordiazepoxide and the bromide salt form of the quaternary ammonium antimuscarinic clidinium with anxiolytic, sedative and antispasmodic activities. Chlordiazepoxide binds to a specific benzodiazepine-binding site on the gamma-aminobutyric acid (GABA)-A receptor in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS. Clidinium binds to and blocks muscarinic receptors in the gastrointestinal (GI) tract. This leads to a decrease in stomach secretions, GI motility and GI spasms." @default.
- NCIT_C87060 NCIT_NHC0 "C87060" @default.
- NCIT_C87060 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C87060 NCIT_P108 "Chlordiazepoxide Hydrochloride/Clidinium Bromide" @default.
- NCIT_C87060 NCIT_P207 "C0064956" @default.
- NCIT_C87060 normalizedInformationContent "100" @default.
- NCIT_C87060 referenceCount "1" @default.
- NCIT_C87060 hasExactSynonym "Chlordiazepoxide Hydrochloride/Clidinium Bromide" @default.
- NCIT_C87060 hasExactSynonym "Librax" @default.
- NCIT_C87060 type Class @default.
- NCIT_C87060 isDefinedBy ncit.owl @default.
- NCIT_C87060 label "Chlordiazepoxide Hydrochloride/Clidinium Bromide" @default.
- NCIT_C87060 subClassOf NCIT_C1908 @default.
- NCIT_C87060 subClassOf NCIT_C1909 @default.
- NCIT_C87060 subClassOf NCIT_C29629 @default.
- NCIT_C87060 subClassOf NCIT_C87060 @default.