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- NCIT_C874 IAO_0000115 "A heat-labile and water-soluble essential vitamin, belonging to the vitamin B family, with antioxidant, erythropoietic, mood modulating, and glucose-regulating activities. Thiamine reacts with adenosine triphosphate (ATP) to form an active coenzyme, thiamine pyrophosphate. Thiamine pyrophosphate is necessary for the actions of pyruvate dehydrogenase and alpha-ketoglutarate in carbohydrate metabolism and for the actions of transketolase, an enzyme that plays an important role in the pentose phosphate pathway. Thiamine plays a key role in intracellular glucose metabolism and may inhibit the action of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine may also protect against lead toxicity by inhibiting lead-induced lipid peroxidation." @default.
- NCIT_C874 NCIT_A5 NCIT_C48025 @default.
- NCIT_C874 NCIT_NHC0 "C874" @default.
- NCIT_C874 NCIT_P106 "Organic Chemical" @default.
- NCIT_C874 NCIT_P106 "Vitamin" @default.
- NCIT_C874 NCIT_P107 "Thiamine" @default.
- NCIT_C874 NCIT_P108 "Thiamine" @default.
- NCIT_C874 NCIT_P207 "C0039840" @default.
- NCIT_C874 NCIT_P210 "59-43-8" @default.
- NCIT_C874 NCIT_P319 "X66NSO3N35" @default.
- NCIT_C874 NCIT_P322 "CRCH" @default.
- NCIT_C874 NCIT_P322 "CTRP" @default.
- NCIT_C874 NCIT_P322 "FDA" @default.
- NCIT_C874 NCIT_P325 "A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Vitamin B1 helps some enzymes work properly, helps break down sugars in the diet, and keeps nerves and the heart healthy. It is found in pork, organ meats, peas, beans, nuts, and whole grains. Vitamin B1 is water-soluble (can dissolve in water) and must be taken in daily. Not enough vitamin B1 can cause a disease called beriberi (a condition marked by heart, nerve, and digestive disorders). Too much vitamin B1 may help cancer cells grow faster." @default.
- NCIT_C874 NCIT_P325 "Water-soluble vitamin that is a coenzyme in the metabolism of carbohydrates and branched-chain amino acids. (DRI)" @default.
- NCIT_C874 NCIT_P329 "37856" @default.
- NCIT_C874 NCIT_P330 "37856" @default.
- NCIT_C874 NCIT_P350 "C12H17N4OS.Cl" @default.
- NCIT_C874 NCIT_P351 "Y" @default.
- NCIT_C874 NCIT_P353 "THIA" @default.
- NCIT_C874 NCIT_P354 "404" @default.
- NCIT_C874 NCIT_P355 "mg" @default.
- NCIT_C874 NCIT_P358 "Y" @default.
- NCIT_C874 NCIT_P359 "Y" @default.
- NCIT_C874 NCIT_P366 "Thiamine" @default.
- NCIT_C874 NCIT_P368 "CHEBI:33283" @default.
- NCIT_C874 NCIT_P399 "37856" @default.
- NCIT_C874 normalizedInformationContent "100" @default.
- NCIT_C874 referenceCount "1" @default.
- NCIT_C874 hasExactSynonym "2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1-thia-3-azoniacyclopenta-2,4-dien-5-yl]ethanol" @default.
- NCIT_C874 hasExactSynonym "Aneurin" @default.
- NCIT_C874 hasExactSynonym "B1 Vitamin" @default.
- NCIT_C874 hasExactSynonym "THIAMINE" @default.
- NCIT_C874 hasExactSynonym "Thiamin" @default.
- NCIT_C874 hasExactSynonym "Thiamine" @default.
- NCIT_C874 hasExactSynonym "Vit B1" @default.
- NCIT_C874 hasExactSynonym "Vitamin B1" @default.
- NCIT_C874 hasExactSynonym "Vitamin-B1" @default.
- NCIT_C874 hasExactSynonym "thiamine" @default.
- NCIT_C874 hasExactSynonym "vitamin B1" @default.
- NCIT_C874 inSubset NCIT_C116977 @default.
- NCIT_C874 inSubset NCIT_C142799 @default.
- NCIT_C874 inSubset NCIT_C176424 @default.
- NCIT_C874 inSubset NCIT_C63923 @default.
- NCIT_C874 type Class @default.
- NCIT_C874 isDefinedBy ncit.owl @default.
- NCIT_C874 label "Thiamine" @default.
- NCIT_C874 subClassOf NCIT_C1551 @default.
- NCIT_C874 subClassOf NCIT_C1908 @default.
- NCIT_C874 subClassOf NCIT_C1930 @default.
- NCIT_C874 subClassOf NCIT_C1949 @default.
- NCIT_C874 subClassOf NCIT_C45812 @default.
- NCIT_C874 subClassOf NCIT_C54060 @default.
- NCIT_C874 subClassOf NCIT_C874 @default.
- NCIT_C874 subClassOf NCIT_C944 @default.