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- NCIT_C87754 IAO_0000115 "A modified form of lipid A, the biologically active part of Gram-negative bacterial lipopolysaccharide (LPS) endotoxin, and a Toll-like receptor 4 (TLR4) agonist, with potential immunostimulatory activity. As a vaccine adjuvant, monophosphoryl lipid A (MPLA) stimulates both cellular and humoral responses to the vaccine antigen. Compared to LPS, MPLA exerts a similar immunostimulatory activity but with reduced toxicity." @default.
- NCIT_C87754 NCIT_NHC0 "C87754" @default.
- NCIT_C87754 NCIT_P106 "Organic Chemical" @default.
- NCIT_C87754 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C87754 NCIT_P108 "Monophosphoryl Lipid A" @default.
- NCIT_C87754 NCIT_P207 "C0066776" @default.
- NCIT_C87754 NCIT_P210 "88598-53-2" @default.
- NCIT_C87754 NCIT_P319 "MWC0ET1L2P" @default.
- NCIT_C87754 NCIT_P322 "FDA" @default.
- NCIT_C87754 NCIT_P329 "732707" @default.
- NCIT_C87754 NCIT_P330 "732707" @default.
- NCIT_C87754 NCIT_P350 "C96H181N2O21P" @default.
- NCIT_C87754 NCIT_P399 "732707" @default.
- NCIT_C87754 normalizedInformationContent "100" @default.
- NCIT_C87754 referenceCount "1" @default.
- NCIT_C87754 hasExactSynonym "3-Deacylated Monophosphoryl Lipid A" @default.
- NCIT_C87754 hasExactSynonym "3-O-Desacyl-4'-Monophosphoryl Lipid A" @default.
- NCIT_C87754 hasExactSynonym "MONOPHOSPHORYL LIPID A" @default.
- NCIT_C87754 hasExactSynonym "MPL" @default.
- NCIT_C87754 hasExactSynonym "MPLA" @default.
- NCIT_C87754 hasExactSynonym "Monophosphoryl Lipid A" @default.
- NCIT_C87754 inSubset NCIT_C176424 @default.
- NCIT_C87754 inSubset NCIT_C63923 @default.
- NCIT_C87754 type Class @default.
- NCIT_C87754 isDefinedBy ncit.owl @default.
- NCIT_C87754 label "Monophosphoryl Lipid A" @default.
- NCIT_C87754 subClassOf NCIT_C1908 @default.
- NCIT_C87754 subClassOf NCIT_C1909 @default.
- NCIT_C87754 subClassOf NCIT_C210 @default.
- NCIT_C87754 subClassOf NCIT_C2140 @default.
- NCIT_C87754 subClassOf NCIT_C308 @default.
- NCIT_C87754 subClassOf NCIT_C87754 @default.