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- NCIT_C88036 IAO_0000115 "An injectable phospholipid emulsion containing the butyrate salt of the synthetic, short-acting, dihydropyridine L-type calcium channel antagonist clevidipine with antihypertensive activity. Clevidipine specifically binds to calcium channels in vascular smooth muscle cells, inhibiting the influx of extracellular calcium ions into vascular smooth muscle cells. This results in dilatation of systemic arteries, a decrease in systemic vascular resistance and so a decrease in arterial blood pressure. This agent is metabolized by esterases in the blood and extravascular tissues to an inactive carboxylic acid metabolite." @default.
- NCIT_C88036 NCIT_NHC0 "C88036" @default.
- NCIT_C88036 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C88036 NCIT_P108 "Clevidipine Butyrate Injectable Emulsion" @default.
- NCIT_C88036 NCIT_P207 "C2981617" @default.
- NCIT_C88036 NCIT_P329 "652185" @default.
- NCIT_C88036 NCIT_P330 "652185" @default.
- NCIT_C88036 NCIT_P399 "652185" @default.
- NCIT_C88036 normalizedInformationContent "100" @default.
- NCIT_C88036 referenceCount "1" @default.
- NCIT_C88036 hasExactSynonym "Clevidipine Butyrate Injectable Emulsion" @default.
- NCIT_C88036 hasExactSynonym "Cleviprex" @default.
- NCIT_C88036 inSubset NCIT_C176424 @default.
- NCIT_C88036 type Class @default.
- NCIT_C88036 isDefinedBy ncit.owl @default.
- NCIT_C88036 label "Clevidipine Butyrate Injectable Emulsion" @default.
- NCIT_C88036 subClassOf NCIT_C1908 @default.
- NCIT_C88036 subClassOf NCIT_C1909 @default.
- NCIT_C88036 subClassOf NCIT_C270 @default.
- NCIT_C88036 subClassOf NCIT_C333 @default.
- NCIT_C88036 subClassOf NCIT_C78274 @default.
- NCIT_C88036 subClassOf NCIT_C88036 @default.
- NCIT_C88036 subClassOf NCIT_C93038 @default.