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NCIT_C88160 IAO_0000115 "Stage IV includes: IVA1 (T1-4, N0-2, M0, B2); IVA2 (T1-4, N3, M0, B0-2); IVB (T1-4, N0-3, M1, B0-2). T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface. May further stratify into T1a (patch only) vs. T1b (plaque +/- patch). T2: Patches, papules, or plaques covering 10% or more of the skin surface. May further stratify into T2a (patch only) vs. T2b (plaque +/- patch). T3: One or more tumors (equal or greater than 1 cm diameter). T4: Confluence of erythema covering 80% or more of body surface area. N0: No clinically abnormal peripheral lymph nodes; biopsy not required. N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2. N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3. N3: Clinically abnormal peripheral lymph nodes; histopathology Dutch grades 3-4 or NCI LN4; clone positive or negative. M0: No visceral organ involvement. M1: Visceral involvement (must have pathology confirmation and organ involved should be specified). B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells). B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2. B2: High blood tumor burden: 1000/microL Sezary cells or more with positive clone. (AJCC 7th ed.)" @default.
NCIT_C88160 NCIT_NHC0 "C88160" @default.
NCIT_C88160 NCIT_P106 "Neoplastic Process" @default.
NCIT_C88160 NCIT_P107 "Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v7" @default.
NCIT_C88160 NCIT_P108 "Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v7" @default.
NCIT_C88160 NCIT_P207 "C0862226" @default.
NCIT_C88160 NCIT_P322 "CTRP" @default.
NCIT_C88160 NCIT_P325 "Stage IV is divided into stages IVA and IVB. In stage IVA, most of the skin is reddened, and any amount of the skin is covered with patches and/or plaques (areas of abnormal tissue) or tumors (lumps of malignant cells). Cancer has spread to lymph nodes, and the lymph nodes may be enlarged. In stage IVB, most of the skin is reddened, and any amount of the skin is covered with lesions or tumors. Cancer has spread to other organs in the body. Lymph nodes may be enlarged and cancer may have spread to them. Stage IV may also be classified based on how many abnormal lymphocytes (white blood cells) are found in the blood." @default.
NCIT_C88160 NCIT_P363 "Malignant" @default.
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