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- NCIT_C88283 IAO_0000115 "A humanized immunoglobulin IgG1 kappa monoclonal antibody directed against the B-cell-specific membrane protein CD-19 with potential immunostimulating and antineoplastic activities. Inebilizumab binds to CD19, which may result in a cytotoxic T-lymphocyte (CTL) response and antibody-dependent cellular cytotoxicity (ADCC) to CD19-expressing B-cells. The Fc portion of inebilizumab does not contain a fucose sugar moiety, which may contribute to its enhanced ADCC activity. CD19 is a membrane antigen that is widely expressed during B-cell development, from pro-B-cell to early plasma cell stages." @default.
- NCIT_C88283 NCIT_A32 NCIT_C1909 @default.
- NCIT_C88283 NCIT_A7 NCIT_C38894 @default.
- NCIT_C88283 NCIT_NHC0 "C88283" @default.
- NCIT_C88283 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C88283 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C88283 NCIT_P107 "Inebilizumab" @default.
- NCIT_C88283 NCIT_P108 "Inebilizumab" @default.
- NCIT_C88283 NCIT_P207 "C2981806" @default.
- NCIT_C88283 NCIT_P210 "1299440-37-1" @default.
- NCIT_C88283 NCIT_P319 "74T7185BMM" @default.
- NCIT_C88283 NCIT_P322 "CTRP" @default.
- NCIT_C88283 NCIT_P322 "FDA" @default.
- NCIT_C88283 NCIT_P322 "GDC" @default.
- NCIT_C88283 NCIT_P329 "656851" @default.
- NCIT_C88283 NCIT_P330 "656851" @default.
- NCIT_C88283 NCIT_P375 "Anti-CD19 Monoclonal Antibody MEDI-551" @default.
- NCIT_C88283 NCIT_P375 "Inebilizumab" @default.
- NCIT_C88283 NCIT_P399 "656851" @default.
- NCIT_C88283 NCIT_R124 NCIT_C17710 @default.
- NCIT_C88283 NCIT_R124 NCIT_C17828 @default.
- NCIT_C88283 NCIT_R124 NCIT_C18219 @default.
- NCIT_C88283 NCIT_R124 NCIT_C19986 @default.
- NCIT_C88283 NCIT_R124 NCIT_C40474 @default.
- NCIT_C88283 normalizedInformationContent "100" @default.
- NCIT_C88283 referenceCount "1" @default.
- NCIT_C88283 hasExactSynonym "INEBILIZUMAB" @default.
- NCIT_C88283 hasExactSynonym "Inebilizumab" @default.
- NCIT_C88283 hasExactSynonym "MEDI-551" @default.
- NCIT_C88283 inSubset NCIT_C116977 @default.
- NCIT_C88283 inSubset NCIT_C116978 @default.
- NCIT_C88283 inSubset NCIT_C128784 @default.
- NCIT_C88283 inSubset NCIT_C157711 @default.
- NCIT_C88283 inSubset NCIT_C157712 @default.
- NCIT_C88283 inSubset NCIT_C176424 @default.
- NCIT_C88283 inSubset NCIT_C177537 @default.
- NCIT_C88283 inSubset NCIT_C63923 @default.
- NCIT_C88283 type Class @default.
- NCIT_C88283 isDefinedBy ncit.owl @default.
- NCIT_C88283 label "Inebilizumab" @default.
- NCIT_C88283 subClassOf NCIT_C112889 @default.
- NCIT_C88283 subClassOf NCIT_C129820 @default.
- NCIT_C88283 subClassOf NCIT_C129821 @default.
- NCIT_C88283 subClassOf NCIT_C129822 @default.
- NCIT_C88283 subClassOf NCIT_C163758 @default.
- NCIT_C88283 subClassOf NCIT_C1908 @default.
- NCIT_C88283 subClassOf NCIT_C1909 @default.
- NCIT_C88283 subClassOf NCIT_C198634 @default.
- NCIT_C88283 subClassOf NCIT_C20401 @default.
- NCIT_C88283 subClassOf NCIT_C274 @default.
- NCIT_C88283 subClassOf NCIT_C307 @default.
- NCIT_C88283 subClassOf NCIT_C308 @default.
- NCIT_C88283 subClassOf NCIT_C88283 @default.