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- NCIT_C88302 IAO_0000115 "An orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. Infigratinib selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. FGFRs are a family of receptor tyrosine kinases which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival." @default.
- NCIT_C88302 NCIT_A32 NCIT_C1909 @default.
- NCIT_C88302 NCIT_A7 NCIT_C17411 @default.
- NCIT_C88302 NCIT_A7 NCIT_C17590 @default.
- NCIT_C88302 NCIT_A7 NCIT_C26129 @default.
- NCIT_C88302 NCIT_NHC0 "C88302" @default.
- NCIT_C88302 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C88302 NCIT_P107 "Infigratinib" @default.
- NCIT_C88302 NCIT_P108 "Infigratinib" @default.
- NCIT_C88302 NCIT_P207 "C2981819" @default.
- NCIT_C88302 NCIT_P210 "872511-34-7" @default.
- NCIT_C88302 NCIT_P319 "A4055ME1VK" @default.
- NCIT_C88302 NCIT_P322 "CTRP" @default.
- NCIT_C88302 NCIT_P322 "FDA" @default.
- NCIT_C88302 NCIT_P322 "GDC" @default.
- NCIT_C88302 NCIT_P368 "CHEBI:63451" @default.
- NCIT_C88302 NCIT_P375 "Infigratinib" @default.
- NCIT_C88302 normalizedInformationContent "100" @default.
- NCIT_C88302 referenceCount "1" @default.
- NCIT_C88302 hasExactSynonym "3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea" @default.
- NCIT_C88302 hasExactSynonym "BGJ-398" @default.
- NCIT_C88302 hasExactSynonym "BGJ398" @default.
- NCIT_C88302 hasExactSynonym "INFIGRATINIB" @default.
- NCIT_C88302 hasExactSynonym "Infigratinib" @default.
- NCIT_C88302 inSubset NCIT_C116977 @default.
- NCIT_C88302 inSubset NCIT_C116978 @default.
- NCIT_C88302 inSubset NCIT_C128784 @default.
- NCIT_C88302 inSubset NCIT_C157711 @default.
- NCIT_C88302 inSubset NCIT_C157712 @default.
- NCIT_C88302 inSubset NCIT_C176424 @default.
- NCIT_C88302 inSubset NCIT_C177537 @default.
- NCIT_C88302 inSubset NCIT_C63923 @default.
- NCIT_C88302 type Class @default.
- NCIT_C88302 isDefinedBy ncit.owl @default.
- NCIT_C88302 label "Infigratinib" @default.
- NCIT_C88302 subClassOf NCIT_C129824 @default.
- NCIT_C88302 subClassOf NCIT_C129825 @default.
- NCIT_C88302 subClassOf NCIT_C1404 @default.
- NCIT_C88302 subClassOf NCIT_C155727 @default.
- NCIT_C88302 subClassOf NCIT_C163758 @default.
- NCIT_C88302 subClassOf NCIT_C164035 @default.
- NCIT_C88302 subClassOf NCIT_C1742 @default.
- NCIT_C88302 subClassOf NCIT_C1908 @default.
- NCIT_C88302 subClassOf NCIT_C1909 @default.
- NCIT_C88302 subClassOf NCIT_C1967 @default.
- NCIT_C88302 subClassOf NCIT_C2189 @default.
- NCIT_C88302 subClassOf NCIT_C274 @default.
- NCIT_C88302 subClassOf NCIT_C471 @default.
- NCIT_C88302 subClassOf NCIT_C88302 @default.