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- NCIT_C90291 IAO_0000115 "A second generation, small-molecule mimetic of ATP that targets the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. PKI-179 selectively inhibits mTOR and phosphoinositide-3-kinase (PI3K) alpha. By inhibiting the PI3K/mTOR signaling pathway, this agent may inhibit tumor cell proliferation and survival." @default.
- NCIT_C90291 NCIT_A32 NCIT_C1909 @default.
- NCIT_C90291 NCIT_A7 NCIT_C30168 @default.
- NCIT_C90291 NCIT_NHC0 "C90291" @default.
- NCIT_C90291 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C90291 NCIT_P108 "PI3Ka/mTOR Inhibitor PKI-179" @default.
- NCIT_C90291 NCIT_P207 "C2933673" @default.
- NCIT_C90291 NCIT_P210 "1197160-28-3" @default.
- NCIT_C90291 NCIT_P319 "CNN7Y60164" @default.
- NCIT_C90291 NCIT_P322 "FDA" @default.
- NCIT_C90291 NCIT_P322 "GDC" @default.
- NCIT_C90291 NCIT_P329 "658412" @default.
- NCIT_C90291 NCIT_P330 "658412" @default.
- NCIT_C90291 NCIT_P375 "PI3Ka/mTOR Inhibitor PKI-179" @default.
- NCIT_C90291 NCIT_P399 "658412" @default.
- NCIT_C90291 normalizedInformationContent "100" @default.
- NCIT_C90291 referenceCount "1" @default.
- NCIT_C90291 hasExactSynonym "PI3Ka/mTOR Inhibitor PKI-179" @default.
- NCIT_C90291 hasExactSynonym "PKI-179" @default.
- NCIT_C90291 inSubset NCIT_C128784 @default.
- NCIT_C90291 inSubset NCIT_C157711 @default.
- NCIT_C90291 inSubset NCIT_C157712 @default.
- NCIT_C90291 inSubset NCIT_C176424 @default.
- NCIT_C90291 inSubset NCIT_C177537 @default.
- NCIT_C90291 inSubset NCIT_C63923 @default.
- NCIT_C90291 type Class @default.
- NCIT_C90291 isDefinedBy ncit.owl @default.
- NCIT_C90291 label "PI3Ka/mTOR Inhibitor PKI-179" @default.
- NCIT_C90291 subClassOf NCIT_C129824 @default.
- NCIT_C90291 subClassOf NCIT_C129825 @default.
- NCIT_C90291 subClassOf NCIT_C1404 @default.
- NCIT_C90291 subClassOf NCIT_C163758 @default.
- NCIT_C90291 subClassOf NCIT_C1742 @default.
- NCIT_C90291 subClassOf NCIT_C1908 @default.
- NCIT_C90291 subClassOf NCIT_C1909 @default.
- NCIT_C90291 subClassOf NCIT_C2152 @default.
- NCIT_C90291 subClassOf NCIT_C2189 @default.
- NCIT_C90291 subClassOf NCIT_C274 @default.
- NCIT_C90291 subClassOf NCIT_C471 @default.
- NCIT_C90291 subClassOf NCIT_C90291 @default.