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- NCIT_C90542 IAO_0000115 "A cancer vaccine consisting of autologous dendritic cells (DCs) transduced with a recombinant adenovirus encoding p53 peptide, with potential immunomodulating activity. Intradermal vaccination with adenoviral-p53 transduced dendritic cell vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. p53, a tumor suppressor gene, is mutated in many tumor cells, resulting in the loss of apoptosis regulation and abnormal cell proliferation." @default.
- NCIT_C90542 NCIT_A7 NCIT_C17387 @default.
- NCIT_C90542 NCIT_NHC0 "C90542" @default.
- NCIT_C90542 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C90542 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C90542 NCIT_P107 "Adenovirus-p53 Transduced Dendritic Cell Vaccine" @default.
- NCIT_C90542 NCIT_P108 "Adenovirus-p53 Transduced Dendritic Cell Vaccine" @default.
- NCIT_C90542 NCIT_P208 "CL416223" @default.
- NCIT_C90542 NCIT_P322 "CTRP" @default.
- NCIT_C90542 NCIT_P329 "664347" @default.
- NCIT_C90542 NCIT_P330 "664347" @default.
- NCIT_C90542 NCIT_P399 "664347" @default.
- NCIT_C90542 normalizedInformationContent "100" @default.
- NCIT_C90542 referenceCount "1" @default.
- NCIT_C90542 hasExactSynonym "Adenovirus-p53 Transduced Dendritic Cell Vaccine" @default.
- NCIT_C90542 hasExactSynonym "Dendritic Cell-P53" @default.
- NCIT_C90542 inSubset NCIT_C116977 @default.
- NCIT_C90542 inSubset NCIT_C116978 @default.
- NCIT_C90542 inSubset NCIT_C128784 @default.
- NCIT_C90542 inSubset NCIT_C176424 @default.
- NCIT_C90542 type Class @default.
- NCIT_C90542 isDefinedBy ncit.owl @default.
- NCIT_C90542 label "Adenovirus-p53 Transduced Dendritic Cell Vaccine" @default.
- NCIT_C90542 subClassOf NCIT_C129820 @default.
- NCIT_C90542 subClassOf NCIT_C1663 @default.
- NCIT_C90542 subClassOf NCIT_C1908 @default.
- NCIT_C90542 subClassOf NCIT_C1909 @default.
- NCIT_C90542 subClassOf NCIT_C274 @default.
- NCIT_C90542 subClassOf NCIT_C28308 @default.
- NCIT_C90542 subClassOf NCIT_C28310 @default.
- NCIT_C90542 subClassOf NCIT_C307 @default.
- NCIT_C90542 subClassOf NCIT_C308 @default.
- NCIT_C90542 subClassOf NCIT_C90542 @default.
- NCIT_C90542 subClassOf NCIT_C923 @default.