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- NCIT_C90555 IAO_0000115 "A plasmid vaccine encoding wild type human carcinoembryonic antigen (CEA) fused to a tetanus toxoid T helper epitope, with potential antineoplastic activity. Upon vaccination and subsequent intradermal electroporation, CEA/tetanus toxoid T helper epitope fusion protein-expressing DNA plasmid vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. CEA, a tumor associated antigen, is overexpressed in a variety of cancer cell types. The tetanus toxoid helper peptide epitope, obtained from the bacterial Clostridium tetani toxoid, binds to class II MHC molecules and increases the helper T-cell response thereby inducing an increased and long-term immune response." @default.
- NCIT_C90555 NCIT_NHC0 "C90555" @default.
- NCIT_C90555 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C90555 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C90555 NCIT_P108 "CEA/Tetanus Toxoid T Helper Epitope Fusion Protein-Expressing DNA Plasmid Vaccine" @default.
- NCIT_C90555 NCIT_P208 "CL416239" @default.
- NCIT_C90555 NCIT_P329 "666096" @default.
- NCIT_C90555 NCIT_P330 "666096" @default.
- NCIT_C90555 NCIT_P399 "666096" @default.
- NCIT_C90555 normalizedInformationContent "100" @default.
- NCIT_C90555 referenceCount "1" @default.
- NCIT_C90555 hasExactSynonym "CEA/Tetanus Toxoid T Helper Epitope Fusion Protein-Expressing DNA Plasmid Vaccine" @default.
- NCIT_C90555 hasExactSynonym "tetwtCEA DNA" @default.
- NCIT_C90555 inSubset NCIT_C128784 @default.
- NCIT_C90555 inSubset NCIT_C176424 @default.
- NCIT_C90555 type Class @default.
- NCIT_C90555 isDefinedBy ncit.owl @default.
- NCIT_C90555 label "CEA/Tetanus Toxoid T Helper Epitope Fusion Protein-Expressing DNA Plasmid Vaccine" @default.
- NCIT_C90555 subClassOf NCIT_C129820 @default.
- NCIT_C90555 subClassOf NCIT_C1663 @default.
- NCIT_C90555 subClassOf NCIT_C1908 @default.
- NCIT_C90555 subClassOf NCIT_C1909 @default.
- NCIT_C90555 subClassOf NCIT_C274 @default.
- NCIT_C90555 subClassOf NCIT_C307 @default.
- NCIT_C90555 subClassOf NCIT_C308 @default.
- NCIT_C90555 subClassOf NCIT_C39619 @default.
- NCIT_C90555 subClassOf NCIT_C90555 @default.
- NCIT_C90555 subClassOf NCIT_C923 @default.