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- NCIT_C90564 IAO_0000115 "An orally bioavailable inhibitor of the proto-oncogene c-Met (also known as hepatocyte growth factor receptor (HGFR)) with potential antineoplastic activity. Capmatinib selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays key roles in tumor cell proliferation, survival, invasion, metastasis, and tumor angiogenesis." @default.
- NCIT_C90564 NCIT_A32 NCIT_C1909 @default.
- NCIT_C90564 NCIT_A5 NCIT_C138995 @default.
- NCIT_C90564 NCIT_A7 NCIT_C18186 @default.
- NCIT_C90564 NCIT_NHC0 "C90564" @default.
- NCIT_C90564 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C90564 NCIT_P107 "Capmatinib" @default.
- NCIT_C90564 NCIT_P108 "Capmatinib" @default.
- NCIT_C90564 NCIT_P208 "CL416248" @default.
- NCIT_C90564 NCIT_P210 "1029712-80-8" @default.
- NCIT_C90564 NCIT_P319 "TY34L4F9OZ" @default.
- NCIT_C90564 NCIT_P322 "CTRP" @default.
- NCIT_C90564 NCIT_P322 "FDA" @default.
- NCIT_C90564 NCIT_P322 "GDC" @default.
- NCIT_C90564 NCIT_P375 "Capmatinib" @default.
- NCIT_C90564 normalizedInformationContent "100" @default.
- NCIT_C90564 referenceCount "1" @default.
- NCIT_C90564 hasExactSynonym "2-Fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide" @default.
- NCIT_C90564 hasExactSynonym "CAPMATINIB" @default.
- NCIT_C90564 hasExactSynonym "Capmatinib" @default.
- NCIT_C90564 hasExactSynonym "INC-280" @default.
- NCIT_C90564 hasExactSynonym "INC280" @default.
- NCIT_C90564 hasExactSynonym "INCB 28060" @default.
- NCIT_C90564 hasExactSynonym "INCB028060" @default.
- NCIT_C90564 hasExactSynonym "INCB28060" @default.
- NCIT_C90564 inSubset NCIT_C116977 @default.
- NCIT_C90564 inSubset NCIT_C116978 @default.
- NCIT_C90564 inSubset NCIT_C128784 @default.
- NCIT_C90564 inSubset NCIT_C157711 @default.
- NCIT_C90564 inSubset NCIT_C157712 @default.
- NCIT_C90564 inSubset NCIT_C177537 @default.
- NCIT_C90564 inSubset NCIT_C63923 @default.
- NCIT_C90564 type Class @default.
- NCIT_C90564 isDefinedBy ncit.owl @default.
- NCIT_C90564 label "Capmatinib" @default.
- NCIT_C90564 subClassOf NCIT_C129824 @default.
- NCIT_C90564 subClassOf NCIT_C129825 @default.
- NCIT_C90564 subClassOf NCIT_C1404 @default.
- NCIT_C90564 subClassOf NCIT_C143099 @default.
- NCIT_C90564 subClassOf NCIT_C163758 @default.
- NCIT_C90564 subClassOf NCIT_C164000 @default.
- NCIT_C90564 subClassOf NCIT_C1908 @default.
- NCIT_C90564 subClassOf NCIT_C1909 @default.
- NCIT_C90564 subClassOf NCIT_C1967 @default.
- NCIT_C90564 subClassOf NCIT_C2189 @default.
- NCIT_C90564 subClassOf NCIT_C274 @default.
- NCIT_C90564 subClassOf NCIT_C471 @default.
- NCIT_C90564 subClassOf NCIT_C90564 @default.