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- NCIT_C908 IAO_0000115 "A synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides. (NCI04)" @default.
- NCIT_C908 NCIT_A5 NCIT_C48028 @default.
- NCIT_C908 NCIT_A5 NCIT_C77554 @default.
- NCIT_C908 NCIT_NHC0 "C908" @default.
- NCIT_C908 NCIT_P106 "Organic Chemical" @default.
- NCIT_C908 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C908 NCIT_P108 "Trimethoprim" @default.
- NCIT_C908 NCIT_P175 "106568" @default.
- NCIT_C908 NCIT_P207 "C0041041" @default.
- NCIT_C908 NCIT_P210 "738-70-5" @default.
- NCIT_C908 NCIT_P319 "AN164J8Y0X" @default.
- NCIT_C908 NCIT_P322 "FDA" @default.
- NCIT_C908 NCIT_P350 "C14H18N4O3" @default.
- NCIT_C908 NCIT_P366 "Trimethoprim" @default.
- NCIT_C908 NCIT_P368 "CHEBI:45924" @default.
- NCIT_C908 normalizedInformationContent "100" @default.
- NCIT_C908 referenceCount "1" @default.
- NCIT_C908 hasExactSynonym "2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine" @default.
- NCIT_C908 hasExactSynonym "Proloprim" @default.
- NCIT_C908 hasExactSynonym "TRIMETHOPRIM" @default.
- NCIT_C908 hasExactSynonym "Trimethoprim" @default.
- NCIT_C908 hasExactSynonym "Trimpex" @default.
- NCIT_C908 inSubset NCIT_C63923 @default.
- NCIT_C908 type Class @default.
- NCIT_C908 isDefinedBy ncit.owl @default.
- NCIT_C908 label "Trimethoprim" @default.
- NCIT_C908 subClassOf NCIT_C1908 @default.
- NCIT_C908 subClassOf NCIT_C1909 @default.
- NCIT_C908 subClassOf NCIT_C254 @default.
- NCIT_C908 subClassOf NCIT_C255 @default.
- NCIT_C908 subClassOf NCIT_C908 @default.