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- NCIT_C91096 IAO_0000115 "An orally available, genetically engineered Salmonella typhimurium strain expressing a truncated form of the human cytokine interleukin-2 (IL-2) gene, with antitumor activity. Upon administration of recombinant attenuated S. typhimurium expressing IL-2 (SalpIL2), this Salmonella strain may selectively accumulate and divide in a variety of tumor types, and express IL-2. In turn, IL-2 may induce natural killer (NK) cell proliferation thereby enhancing their activity. This may inhibit the growth of tumor cells." @default.
- NCIT_C91096 NCIT_NHC0 "C91096" @default.
- NCIT_C91096 NCIT_P106 "Bacterium" @default.
- NCIT_C91096 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C91096 NCIT_P107 "Recombinant Attenuated Salmonella typhimurium Expressing IL-2" @default.
- NCIT_C91096 NCIT_P108 "Recombinant Attenuated Salmonella typhimurium Expressing IL-2" @default.
- NCIT_C91096 NCIT_P208 "CL421482" @default.
- NCIT_C91096 NCIT_P322 "CTRP" @default.
- NCIT_C91096 NCIT_P329 "672505" @default.
- NCIT_C91096 NCIT_P330 "672505" @default.
- NCIT_C91096 NCIT_P399 "672505" @default.
- NCIT_C91096 normalizedInformationContent "100" @default.
- NCIT_C91096 referenceCount "1" @default.
- NCIT_C91096 hasExactSynonym "Recombinant Attenuated Salmonella typhimurium Expressing IL-2" @default.
- NCIT_C91096 inSubset NCIT_C116977 @default.
- NCIT_C91096 inSubset NCIT_C116978 @default.
- NCIT_C91096 inSubset NCIT_C128784 @default.
- NCIT_C91096 inSubset NCIT_C176424 @default.
- NCIT_C91096 type Class @default.
- NCIT_C91096 isDefinedBy ncit.owl @default.
- NCIT_C91096 label "Recombinant Attenuated Salmonella typhimurium Expressing IL-2" @default.
- NCIT_C91096 subClassOf NCIT_C129821 @default.
- NCIT_C91096 subClassOf NCIT_C1908 @default.
- NCIT_C91096 subClassOf NCIT_C1909 @default.
- NCIT_C91096 subClassOf NCIT_C1962 @default.
- NCIT_C91096 subClassOf NCIT_C274 @default.
- NCIT_C91096 subClassOf NCIT_C307 @default.
- NCIT_C91096 subClassOf NCIT_C61199 @default.
- NCIT_C91096 subClassOf NCIT_C91096 @default.