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- NCIT_C91328 NCIT_NHC0 "C91328" @default.
- NCIT_C91328 NCIT_P106 "Functional Concept" @default.
- NCIT_C91328 NCIT_P108 "Formation of Ketone Bodies from Acetyl-CoA Pathway" @default.
- NCIT_C91328 NCIT_P207 "C2984168" @default.
- NCIT_C91328 NCIT_P216 "ketonebodiesPathway" @default.
- NCIT_C91328 NCIT_P325 "The acetyl-CoA produced by mitochondrial beta-oxidation of fatty acids enters the Kreb's cycle to produce energy, but that is not the only fate of acetyl-CoA. In liver mitochondria, some acetyl-CoA is converted to acetoacetate, beta-hydroxybutyrate, and acetone, collectively called ketone bodies. Ketone bodies are transported to other tissues such as brain, muscle or heart where they are converted back to acetyl-CoA to serve as an energy source. The brain normally uses only glucose for energy, but during starvation ketone bodies can become the main energy source for the brain. In the metabolic condition called ketosis, ketone bodies are produced faster than they are consumed by tissues and the smell of acetone can be detected on a person's breath. The smell of acetone is one indication that a person may have diabetes. The consumption of high-fat/low carbohydrate diets has been used as a weight loss program by many, intentionally inducing ketosis to consume fat stores, but these ketogenic diets can cause unwanted side effects related to increased urea production resulting from protein intake and risk of heart disease from increased cholesterol and fat intake. (This definition may be outdated - see the DesignNote.)" @default.
- NCIT_C91328 NCIT_P98 "The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/." @default.
- NCIT_C91328 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C91328 referenceCount "3" @default.
- NCIT_C91328 hasExactSynonym "Formation of Ketone Bodies from Acetyl-CoA Pathway" @default.
- NCIT_C91328 hasExactSynonym "Formation of Ketone Bodies from Acetyl-CoA" @default.
- NCIT_C91328 type Class @default.
- NCIT_C91328 isDefinedBy ncit.owl @default.
- NCIT_C91328 label "Formation of Ketone Bodies from Acetyl-CoA Pathway" @default.
- NCIT_C91328 subClassOf NCIT_C18611 @default.
- NCIT_C91328 subClassOf NCIT_C20633 @default.
- NCIT_C91328 subClassOf NCIT_C39734 @default.
- NCIT_C91328 subClassOf NCIT_C91328 @default.