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- NCIT_C91377 IAO_0000115 "A trivalent cancer vaccine containing the ganglioside lactones GM2, GD2 and GD3 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with GM2 lactone/GD2 lactone/GD3 lactone-KLH conjugate trivalent vaccine may elicit antibodies against tumor cells expressing any of these epitopes, resulting in an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing these gangliosides. GM2, GD2 and GD3 are tumor associated antigens (TAAs) that are overexpressed in a variety of tumor cell membranes." @default.
- NCIT_C91377 NCIT_A7 NCIT_C1110 @default.
- NCIT_C91377 NCIT_A7 NCIT_C39782 @default.
- NCIT_C91377 NCIT_A7 NCIT_C516 @default.
- NCIT_C91377 NCIT_NHC0 "C91377" @default.
- NCIT_C91377 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C91377 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C91377 NCIT_P107 "GM2/GD2/GD3 Lactone-KLH Conjugate Trivalent Vaccine" @default.
- NCIT_C91377 NCIT_P108 "GM2/GD2/GD3 Lactone-KLH Conjugate Trivalent Vaccine" @default.
- NCIT_C91377 NCIT_P208 "CL421633" @default.
- NCIT_C91377 NCIT_P322 "CTRP" @default.
- NCIT_C91377 NCIT_P329 "680847" @default.
- NCIT_C91377 NCIT_P330 "680847" @default.
- NCIT_C91377 NCIT_P399 "680847" @default.
- NCIT_C91377 normalizedInformationContent "100" @default.
- NCIT_C91377 referenceCount "1" @default.
- NCIT_C91377 hasExactSynonym "GM2/GD2/GD3 Lactone-KLH Conjugate Trivalent Vaccine" @default.
- NCIT_C91377 inSubset NCIT_C116977 @default.
- NCIT_C91377 inSubset NCIT_C116978 @default.
- NCIT_C91377 inSubset NCIT_C128784 @default.
- NCIT_C91377 inSubset NCIT_C176424 @default.
- NCIT_C91377 type Class @default.
- NCIT_C91377 isDefinedBy ncit.owl @default.
- NCIT_C91377 label "GM2/GD2/GD3 Lactone-KLH Conjugate Trivalent Vaccine" @default.
- NCIT_C91377 subClassOf NCIT_C1455 @default.
- NCIT_C91377 subClassOf NCIT_C1908 @default.
- NCIT_C91377 subClassOf NCIT_C1909 @default.
- NCIT_C91377 subClassOf NCIT_C307 @default.
- NCIT_C91377 subClassOf NCIT_C308 @default.
- NCIT_C91377 subClassOf NCIT_C91377 @default.
- NCIT_C91377 subClassOf NCIT_C923 @default.