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- NCIT_C91385 IAO_0000115 "A fully human IgG1 monoclonal antibody directed against B-Lymphocyte stimulator protein (BlyS or TNFSF13B) with potential immunomodulating activity. Belimumab specifically recognizes and inhibits the biological activity of BlyS, thereby preventing the binding of BlyS to B-lymphocytes. This inhibits the maturation of B-lymphocytes and may induce apoptosis in B-lymphocytes. In addition, it may decrease B-lymphocyte proliferation and/or survival. BlyS, a member of TNF family supporting B-lymphocyte maturation and survival, has been implicated in the pathogenesis of autoimmune diseases and B-lymphocyte malignancies." @default.
- NCIT_C91385 NCIT_A32 NCIT_C1909 @default.
- NCIT_C91385 NCIT_A7 NCIT_C94789 @default.
- NCIT_C91385 NCIT_NHC0 "C91385" @default.
- NCIT_C91385 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C91385 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C91385 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C91385 NCIT_P107 "Belimumab" @default.
- NCIT_C91385 NCIT_P108 "Belimumab" @default.
- NCIT_C91385 NCIT_P207 "C1723401" @default.
- NCIT_C91385 NCIT_P210 "356547-88-1" @default.
- NCIT_C91385 NCIT_P302 "Systemic Lupus Erythematosus" @default.
- NCIT_C91385 NCIT_P319 "73B0K5S26A" @default.
- NCIT_C91385 NCIT_P322 "CTRP" @default.
- NCIT_C91385 NCIT_P322 "FDA" @default.
- NCIT_C91385 NCIT_P322 "GDC" @default.
- NCIT_C91385 NCIT_P329 "680522" @default.
- NCIT_C91385 NCIT_P330 "680522" @default.
- NCIT_C91385 NCIT_P375 "Belimumab" @default.
- NCIT_C91385 NCIT_P399 "680522" @default.
- NCIT_C91385 NCIT_R124 NCIT_C17710 @default.
- NCIT_C91385 NCIT_R124 NCIT_C17828 @default.
- NCIT_C91385 NCIT_R124 NCIT_C18219 @default.
- NCIT_C91385 NCIT_R124 NCIT_C19986 @default.
- NCIT_C91385 NCIT_R124 NCIT_C40474 @default.
- NCIT_C91385 normalizedInformationContent "100" @default.
- NCIT_C91385 referenceCount "1" @default.
- NCIT_C91385 hasExactSynonym "BELIMUMAB" @default.
- NCIT_C91385 hasExactSynonym "Belimumab" @default.
- NCIT_C91385 hasExactSynonym "Benlysta" @default.
- NCIT_C91385 hasExactSynonym "Immunoglobulin G1, anti-(Human Cytokine BAFF) (Human Monoclonal LymphoStat-B Heavy Chain), Disulfide with Human Monoclonal LymphoStat-B lambda-chain, Dimer" @default.
- NCIT_C91385 hasExactSynonym "LymphoStat-B" @default.
- NCIT_C91385 inSubset NCIT_C116977 @default.
- NCIT_C91385 inSubset NCIT_C116978 @default.
- NCIT_C91385 inSubset NCIT_C128784 @default.
- NCIT_C91385 inSubset NCIT_C157711 @default.
- NCIT_C91385 inSubset NCIT_C157712 @default.
- NCIT_C91385 inSubset NCIT_C176424 @default.
- NCIT_C91385 inSubset NCIT_C177537 @default.
- NCIT_C91385 inSubset NCIT_C63923 @default.
- NCIT_C91385 type Class @default.
- NCIT_C91385 isDefinedBy ncit.owl @default.
- NCIT_C91385 label "Belimumab" @default.
- NCIT_C91385 subClassOf NCIT_C1908 @default.
- NCIT_C91385 subClassOf NCIT_C1909 @default.
- NCIT_C91385 subClassOf NCIT_C20401 @default.
- NCIT_C91385 subClassOf NCIT_C307 @default.
- NCIT_C91385 subClassOf NCIT_C308 @default.
- NCIT_C91385 subClassOf NCIT_C91385 @default.